Acquired bloodstream infection in the intensive care unit: incidence and attributable mortality

Table 4 Cox-proportional hazard analysis for hospital survival

Risk Factor	Hazard Ratio	95% CI	P
APACHE III (factor/point)	1.02	1.02-1.02	< 0.001
Age (factor/year*)	1.01	1.01-1.01	< 0.001
Acquired BSI	2.89	2.41-3.46	< 0.001
Surgical Admission	0.78	0.71-0.87	< 0.001
Liver Disease	1.34	1.12-1.61	0.001
Malignancy	1.23	1.08-1.40	0.002
Mechanical Ventilation	1.13	1.00-1.26	0.041
Immune Deficiency	1.18	0.99-1.40	0.059
Chronic Kidney Disease	1.18	0.94-1.48	0.148
Chronic Pulmonary Disease	1.15	0.95-1.39	0.162
Insulin-Requiring Diabetes Mellitus	1.18	0.90-1.54	0.221
Renal Replacement Therapy	1.09	0.92-1.30	0.334
Male Sex	0.98	0.89-1.09	0.767

APACHE, Acute Physiology and Chronic Health Evaluation; BSI, bloodstream infection; CI, confidence interval.
*Hazard ratio of 1.01/year equates to a 1.1 times hazard for death with a ten year increase in age.

ISSN: 1364-8535