Table 2 Comparison of immunological parameters based upon ICU mortality
From: Early natural killer cell counts in blood predict mortality in severe sepsis
ICU mortality from day 1 (N= 50) | ICU mortality from day 3 (N= 40) | ICU mortality from day 10 (N= 37) | |||||||
|---|---|---|---|---|---|---|---|---|---|
Immunological parameters | Survivors ( n = 29) | Nonsurvivors ( n = 21) | P value | Survivors ( n = 29) | Nonsurvivors ( n = 11) | P value | Survivors ( n = 28) | Nonsurvivors ( n = 9) | P value |
IgG (mg/dl) | 844.0 (447.5) | 616.0 (442.5) | 0.035 | 932.0 (371.0) | 685.0 (538.0) | 0.007 | 1,080.0 (602.2) | 764.0 (1068.0) | n.s. |
IgA (mg/dl) | 240.0 (128.0) | 184.0 (167.0) | n.s. | 280.0 (144.0) | 240.0 (209.0) | n.s. | 334.0 (164.0) | 257.0 (580.8) | n.s. |
IgM (mg/dl) | 53.0 (47.0) | 60.0 (53.0) | n.s. | 70.0 (85.0) | 67.0 (61.0) | n.s. | 79.5 (66.5) | 42.0 (86.0) | n.s. |
C3 (mg/dl) | 101.5 (52.3) | 79.0 (60.5) | n.s. | 108.0 (55.0) | 110.0 (89.0) | n.s. | 135.0 (49.0) | 106.0 (81.0) | n.s. |
C4 (mg/dl) | 24.0 (19.0) | 17.0 (16.0) | 0.029 | 24.0 (16.5) | 28.0 (22.0) | n.s. | 32.0 (18.0) | 20.0 (10.0) | n.s. |
CD3+ T (cells/mm3) | 417.0 (706.5) | 419.0 (585.0) | n.s. | 639.5 (636.3) | 472.0 (415.0) | n.s. | 774.0 (463.5) | 561.0 (552.0) | n.s. |
CD4+ T (cells/mm3) | 288.0 (474.5) | 198.0 (400.0) | n.s. | 372.5 (525.8) | 366.0 (423.0) | n.s. | 519.0 (339.0) | 347.0 (355.0) | n.s. |
CD8+ T (cells/mm3) | 114.0 (258.0) | 156.0 (231.0) | n.s. | 249.5 (199.0) | 120.0 (145.0) | n.s. | 287.0 (296.0) | 204.0 (314.0) | n.s. |
CD4+ CD8+ T (cells/mm3) | 5.0 (12.0) | 6.0 (13.5) | n.s. | 5.0 (9.0) | 6.5 (24.0) | n.s. | 12.0 (18.3) | 6.0 (54.0) | n.s. |
LB (cells/mm3) | 103.0 (165.5) | 184.0 (281.0) | n.s. | 163.0 (125.0) | 127.0 (168.0) | n.s. | 118.0 (151.0) | 92.0 (131.0) | n.s. |
NK (cells/mm3) | 56.8 (59.5) | 98.0 (392.0) | 0.050 | 59.5 (72.5) | 42.0 (73.0) | n.s. | 86.0 (78.0) | 92.0 (38.0) | n.s. |