Characteristics | Survivors (n = 50) | Decedents (n = 50) | P |
---|---|---|---|
Age (years) | 71.6 ± 10.8 | 71.3 ± 13.6 | 0.63 |
Females, n (%) | 23 (46) | 23 (46) | 1.00 |
BMI (kg/m2) | 25.5 ± 4.9 | 28.4 ± 7.6 | 0.09 |
Randomized to albumin, n (%) | 27 (54) | 27 (54) | 1.00 |
Source of severe sepsis, n (%) | |||
Lungs | 19 (38) | 19 (38) | 1.00 |
Abdomen | 26 (52) | 20 (40) | 0.23 |
Urinary tract | 8 (16) | 10 (20) | 0.60 |
Other | 7 (14) | 10 (20) | 0.42 |
SAPS II score | 50 ± 14 | 51 ± 12 | 0.75 |
SOFA score | 8 (6 to 10) | 9 (7 to 11) | 0.10 |
Reason for ICU admission, n (%) | |||
Medical | 25 (50) | 28 (56) | 0.55 |
Emergency surgery | 23 (46) | 17 (34) | 0.22 |
Elective surgery | 2 (4) | 5 (10) | 0.44 |
Shock, n (%) | 40 (80) | 34 (68) | 0.17 |
Mechanical ventilation, n (%) | 44 (88) | 45 (90) | 0.75 |
Vasoactive drugs, n (%) | 37 (74) | 36 (72) | 0.82 |
Heart rate (beats/min) | 102 ± 27 | 103 ± 21 | 0.91 |
Mean arterial pressure (mmHg) | 73 ± 16 | 73 ± 14 | 0.78 |
Central venous pressure (mmHg) | 8.0 (6.0 to 13.7) | 9.9 (7.3 to 12.5) | 0.54 |
Central venous oxygen saturation (%) | 75 (66 to 81) | 73 (66 to 80) | 0.53 |
Urine output (ml/h) | 40 (16 to 100) | 50 (20 to 90) | 0.94 |
Serum lactate (mmol/L) | 2.6 (1.6 to 4.2) | 2.5 (1.8 to 4.2) | 0.67 |
Plasma presepsin on day 1 (pg/ml) | 1,184 (875 to 2,113) | 2,269 (1,171 to 4,300) | 0.0015 |
Plasma procalcitonin on day 1 (μg/L) | 10.8 (2.7 to 41.9) | 18.5 (3.4 to 45.2) | 0.31 |