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Table 1 Baseline clinical characteristics and biomarkers in survivors and nonsurvivors at ICU discharge a

From: Presepsin (soluble CD14 subtype) and procalcitonin levels for mortality prediction in sepsis: data from the Albumin Italian Outcome Sepsis trial

Characteristics

Survivors (n = 50)

Decedents (n = 50)

P

Age (years)

71.6 ± 10.8

71.3 ± 13.6

0.63

Females, n (%)

23 (46)

23 (46)

1.00

BMI (kg/m2)

25.5 ± 4.9

28.4 ± 7.6

0.09

Randomized to albumin, n (%)

27 (54)

27 (54)

1.00

Source of severe sepsis, n (%)

   

 Lungs

19 (38)

19 (38)

1.00

 Abdomen

26 (52)

20 (40)

0.23

 Urinary tract

8 (16)

10 (20)

0.60

 Other

7 (14)

10 (20)

0.42

SAPS II score

50 ± 14

51 ± 12

0.75

SOFA score

8 (6 to 10)

9 (7 to 11)

0.10

Reason for ICU admission, n (%)

   

 Medical

25 (50)

28 (56)

0.55

 Emergency surgery

23 (46)

17 (34)

0.22

 Elective surgery

2 (4)

5 (10)

0.44

Shock, n (%)

40 (80)

34 (68)

0.17

Mechanical ventilation, n (%)

44 (88)

45 (90)

0.75

Vasoactive drugs, n (%)

37 (74)

36 (72)

0.82

Heart rate (beats/min)

102 ± 27

103 ± 21

0.91

Mean arterial pressure (mmHg)

73 ± 16

73 ± 14

0.78

Central venous pressure (mmHg)

8.0 (6.0 to 13.7)

9.9 (7.3 to 12.5)

0.54

Central venous oxygen saturation (%)

75 (66 to 81)

73 (66 to 80)

0.53

Urine output (ml/h)

40 (16 to 100)

50 (20 to 90)

0.94

Serum lactate (mmol/L)

2.6 (1.6 to 4.2)

2.5 (1.8 to 4.2)

0.67

Plasma presepsin on day 1 (pg/ml)

1,184 (875 to 2,113)

2,269 (1,171 to 4,300)

0.0015

Plasma procalcitonin on day 1 (μg/L)

10.8 (2.7 to 41.9)

18.5 (3.4 to 45.2)

0.31

  1. aBMI, Body mass index; SAPS II, Simplified Acute Physiology Score II; SOFA, Sequential Organ Failure Assessment. Continuous variables are presented as mean ± SD or median and interquartile range when not normally distributed. Categorical variables are presented as number (%).