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Table 2 Clinical and infectious characteristics of all patients with an ICU LOS of more than24 hours

From: Brazilian Sepsis Epidemiological Study (BASES study)

Characteristic

Center 1

Center 2

Center 3

Center 4

Center 5

Total

Enrolled patients (n)

359

146

125

76

178

884

Median age (IQR)

73.6 (58.5–81.5)

55.4 (42.5–60.6)

47.6 (32.0–66.9)

61.4 (44.2–68.7)

68.9 (57.8–77.1)

66.4 (49.2–77.1)

Male/female (%)

62/38

59/41

59/41

62/38

51/49

59/41

Median APACHE II score (IQR)

16 (11–21)

17.5 (9.7–25.2)

16 (12–20)

16 (10–20)

18 (14–21)

17 (11–22)

First-day SOFA score (IQR)

3 (1–5)

6 (2.7–9)

6 (3–8)

4 (2–7)

6 (4–9)

4 (2–8)

Median ICU LOS, days (IQR)

3 (2–7)

5.5 (3–10.2)

6 (3–12)

3 (2–7.7)

4 (2–10)

4 (2–9)

Main ICU admission diagnosis

      

   Respiratory infection, n (%)

43 (11.9)

16 (10.9)

10 (8.0)

12 (15.8)

42 (23.6)

123 (13.9)

   Acute coronary syndrome, n (%)

52 (14.5)

24 (16.4)

4 (3.2)

25 (32.9)

2 (1.1)

107 (12.0)

   GI postoperative patients, n (%)

9 (2.5)

11 (7.5)

5 (4.0)

7 (9.2)

50 (28.1)

82 (9.3)

   Sepsis, n (%)

34 (9.5)

2 (1.4)

17 (13.6)

3 (3.9)

13 (7.3)

69 (7.8)

   GI surgery for neoplasm, n (%)

22 (6.1)

4 (2.7)

4 (3.2)

7 (9.2)

25 (14.0)

62 (7.0)

   Cardiovascular surgery, n (%)

38 (10.6)

1 (0.06)

4 (3.2)

-

18 (10.1)

61 (6.9)

   Clinical neurological disorders, n (%)

36 (10.0)

10 (6.8)

6 (4.8)

-

5 (02.8)

57 (6.4)

Site of infection

      

   Lung, n (%)

86 (72.3)

30 (43.5)

52 (67.5)

24 (68.5)

75 (70.1)

267 (65.6)

   Urinary tract, n (%)

9 (7.6)

4 (5.7)

5 (6.5)

-

5 (4.7)

23 (5.6)

   Abdomen/surgical wound, n (%)

4 (3.3)

5 (7.3)

-

5 (14.3)

6 (5.6)

20 (4.9)

   Bloodstream, n (%)

5 (4.2)

1 (1.5)

1 (1.3)

3 (8.6)

21 (19.6)

10 (2.5)

   Other/unknown, n (%)

15 (12.6)

29 (42.2)

19 (24.7)

3 (8.6)

21 (19.6)

87 (21.4)

   Diagnosed infections, n (%)

119 (100)

69 (100)

77 (100)

35 (100)

107 (100)

407 (100)

Enrolled patients, n

      

   Consensus Conference Diagnosis

359

146

125

76

178

884 (100%)

   SIRS

291

130

122

74

168

785 (88.8%)

   Sepsis

121

72

79

34

109

415 (46.9%)

   Severe sepsis

57

38

46

191

81

241 (27.3%)

   Septic shock

42

34

39

16

72

203 (23.0%)

Overall mortality rate (%)

12.5

32.2

23.7

24.8

31.4

22.3

  1. GI, gastrointestinal; IQR, interquartile range; LOS, length of stay; SIRS, systemic inflammatory response syndrome; SOFA, sequential organ failure assessment.