Skip to main content

Table 4 Characteristics of treatment and outcome in 20 patients with Aspergillus spp. infection

From: Isolation of Aspergillus spp. from the respiratory tract in critically ill patients: risk factors, clinical presentation and outcome

Case

APACHE II score at start of treatment

Antifungal agent

Total doses (mg)

Days of treatment

Microbiological eradication

Clinical cure

Outcome

1

18

Liposomal amphotericin B

2450

21

Yes

Yes

Alive

2

29

Itraconazole

-

5

?

No

Death in the ICU

3

17

Liposomal amphotericin B

3100

21

?

Yes

Alive

4

17

Liposomal amphotericin B

2650

17

Yes

Yes

Death in the hospital

5

20

Liposomal amphotericin B

600

4

?

No

Death in the ICU

6

16

Amphotericin B deoxycholate

450

10

No

No

Alive

7

?

Amphotericin B deoxycholate

1050

21

Yes

Yes

Alive

8

23

Amphotericin B deoxycholate

180

5

?

No

Death in the ICU

9

20

Amphotericin B deoxycholate

1050

7

No

No

Death in the ICU

10

19

Amphotericin B lipid complex

2300

9

No

No

Death in the ICU

11

22

Liposomal amphotericin B

3180

21

?

No

Death in the ICU

12

22

Liposomal amphotericin B

3300

15

Yes

Yes

Death in the ICU

13

11

Amphotericin B deoxycholate/liposomal amphotericin B

1200/1200

12/4

No

No

Death in the ICU

14

32

Liposomal amphotericin B

4000

16

Yes

Yes

Death in the ICU

15

45

Amphotericin B lipid complex

2400

8

?

Yes

Alive

16

16

Amphotericin B deoxycholate/amphotericin B lipid complex

350/300

6/2

No

No

Death in the ICU

17

25

Amphotericin B lipid complex/liposomal amphotericin B

3600/6300

14/21

No/Yes

No/Yes

Death in the ICU

18

?

Amphotericin B deoxycholate

420

7

?

No

Death in the ICU

19

34

Amphotericin B deoxycholate

450

7

?

No

Death in the ICU

20

23

Liposomal amphotericin B

2200

11

Yes

Yes

Alive

  1. APACHE, Acute Physiology and Chronic Health Evaluation; ICU, intensive care unit.