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The Gliding-SLICE method: an enhanced tool for estimation of intratidal respiratory mechanics

Introduction

Focusing on lung-protective ventilation, the analysis of nonlinear dynamic respiratory mechanics appears crucial. Based on the SLICE method we developed the Gliding-SLICE method as a tool to determine respiratory system mechanics. This tool was tested in a nonlinear water-filled two-chamber lung model.

Methods

The classic SLICE method [1] determines parameters of the respiratory system for abutted volume ranges. The Gliding-SLICE method enhances this method by moving a window of analysis along the volume axis. This way, a quasi-continual course of intratidal mechanics can be determined. To test the new method we build up a physical model that consists of two connected chambers filled with water. During inspiration water is displaced from one chamber to the other resulting in a counter pressure. Using wedges of certain shapes we simulated volume-dependent nonlinear compliances.

Results

Using the Gliding-SLICE method we determined a nonlinear course of compliance in a patient (Figure 1) and in model data (Figure 2).

Figure 1
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Figure 2
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Conclusion

The Gliding-SLICE method allows one to calculate mechanical parameters of the respiratory system quasi-continually. This allows a more intuitive interpretation of data. The method is not limited to principle constrictions but can be enhanced by ventilatory maneuvers; for example, for separated view on inspiratory and expiratory respiratory mechanics.

References

  1. 1.

    Guttmann , et al.: Technol Health Care. 1994, 2: 175-191.

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Schumann, S., Stahl, C., Steinmann, D. et al. The Gliding-SLICE method: an enhanced tool for estimation of intratidal respiratory mechanics. Crit Care 11, P204 (2007). https://0-doi-org.brum.beds.ac.uk/10.1186/cc5364

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Keywords

  • Model Data
  • System Mechanic
  • Respiratory System
  • Mechanical Parameter
  • Volume Range