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Influence of ABO blood group polymorphism on mortality in intensive care unit patients
Critical Care volume 11, Article number: P446 (2007)
Blood groups may be related to differences in inflammatory responses . We looked at blood group as a risk factor for ICU mortality in general and for patients with sepsis.
Data were retrospectively collected from all 11,553 patients that were admitted from 1997 to 2005 to our medical/surgical ICU.
ICU mortality and SAPS II score for different blood groups are shown in Table 1. P values are given for the difference between blood groups A and O. No differences were found for age, gender, and reason for admission. No influence of rhesus blood group type was seen on mortality.
Blood group O is associated with a higher ICU mortality rate than blood group A. The relative risk increase for ICU mortality was 18% for all patients and 30% for patients with severe sepsis.
Garratty G: Transfusion Med Rev. 2000, 14: 291. 10.1053/tmrv.2000.16228
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Seubert, M. Influence of ABO blood group polymorphism on mortality in intensive care unit patients. Crit Care 11, P446 (2007). https://0-doi-org.brum.beds.ac.uk/10.1186/cc5606
- Public Health
- Mortality Rate
- Intensive Care Unit
- Relative Risk
- Inflammatory Response