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Influence of ABO blood group polymorphism on mortality in intensive care unit patients

Introduction

Blood groups may be related to differences in inflammatory responses [1]. We looked at blood group as a risk factor for ICU mortality in general and for patients with sepsis.

Methods

Data were retrospectively collected from all 11,553 patients that were admitted from 1997 to 2005 to our medical/surgical ICU.

Results

ICU mortality and SAPS II score for different blood groups are shown in Table 1. P values are given for the difference between blood groups A and O. No differences were found for age, gender, and reason for admission. No influence of rhesus blood group type was seen on mortality.

Table 1 (abstract P446)

Conclusion

Blood group O is associated with a higher ICU mortality rate than blood group A. The relative risk increase for ICU mortality was 18% for all patients and 30% for patients with severe sepsis.

References

  1. 1.

    Garratty G: Transfusion Med Rev. 2000, 14: 291. 10.1053/tmrv.2000.16228

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Seubert, M. Influence of ABO blood group polymorphism on mortality in intensive care unit patients. Crit Care 11, P446 (2007). https://0-doi-org.brum.beds.ac.uk/10.1186/cc5606

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Keywords

  • Public Health
  • Mortality Rate
  • Intensive Care Unit
  • Relative Risk
  • Inflammatory Response