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Table 2 Classification/staging system for acute kidney injurya

From: Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury

Stage Serum creatinine criteria Urine output criteria
1 Increase in serum creatinine of more than or equal to 0.3 mg/dl (≥ 26.4 μmol/l) or increase to more than or equal to 150% to 200% (1.5- to 2-fold) from baseline Less than 0.5 ml/kg per hour for more than 6 hours
2b Increase in serum creatinine to more than 200% to 300% (> 2- to 3-fold) from baseline Less than 0.5 ml/kg per hour for more than 12 hours
3c Increase in serum creatinine to more than 300% (> 3-fold) from baseline (or serum creatinine of more than or equal to 4.0 mg/dl [≥ 354 μmol/l] with an acute increase of at least 0.5 mg/dl [44 μmol/l]) Less than 0.3 ml/kg per hour for 24 hours or anuria for 12 hours
  1. aModified from RIFLE (Risk, Injury, Failure, Loss, and End-stage kidney disease) criteria [26]. The staging system proposed is a highly sensitive interim staging system and is based on recent data indicating that a small change in serum creatinine influences outcome. Only one criterion (creatinine or urine output) has to be fulfilled to qualify for a stage. b200% to 300% increase = 2- to 3-fold increase. cGiven wide variation in indications and timing of initiation of renal replacement therapy (RRT), individuals who receive RRT are considered to have met the criteria for stage 3 irrespective of the stage they are in at the time of RRT.