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Table 2 Common toxidromes in illicit drug use

From: Clinical review: Major consequences of illicit drug consumption

Toxidrome Features Drugs implicated
Adrenergic Hypertension, tachycardia, mydriasis, diaphoresis, agitation, dry mucus membranes Amphetamines, cocaine, ephedrine, phencyclidine
Sedative Stupor and coma, confusion, slurred speech, apnea Barbiturates, benzodiazepines, ethanol, opiates
Hallucinogenic Hallucinations, psychosis, panic, fever, hyperthermia Amphetamines, cannabinoids, cocaine
Narcotic Altered mental status, slow shallow breaths, miosis, bradycardia, hypotension, hypothermia, decreased bowel sounds Opiates
Epileptogenic Hyperthermia, hyperrreflexia, tremors, seizures Cocaine, phencyclidine
  1. Adapted from [35].
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