From: Diagnosis of ventilator-associated pneumonia: a systematic review of the literature
First author | Sample | Dx Tests | Gold standard | Results |
---|---|---|---|---|
Povoa, 2005, # [73] | Mixed ICU, 112 pts | CRP | Johanson | CRP (>9.6 mg/dl): sens = 87%, spec = 88%, AUC = 0.92. |
Gibot, 2004, ** [75] | Mixed ICU, 148 pts | sTREM-1 in mini-BAL | Mini-BAL (103) Clinical (ad hoc) | Sens = 98%, spec = 90%. |
Duflo, 2002, ** [71] | Mixed ICU, 96 pts | PCT serum & alveolar | Mini-BAL (103) | Serum PCT (≥3.9 ng/ml): sens = 41%, spec = 100%, AUC = 0787. Alveolar PCT: not useful. |
Oppert, 2002, ** [72] | Mixed ICU, 28 pts | PCT and PCR | Clinical (ad hoc) | Serum PCT (>1 ng/ml): sens = 100%, spec = 75%. |
El-Ebiary, 1995, *, ** [69] | Mixed ICU, 78 pts | Elastin fibre | Clinical (ad hoc) | EF: sens = 32%, spec = 72%. |
Determann, 2005, ** [76] | Mixed ICU, 28 pts | sTREM-1 | Clinical & NBLF | Sens = 75%, spec = 84%. |
Pugin, 1992, ** [78] | Trauma ICU, 40 pts | BAL Endotoxin | Clinical & BAL | BAL endotoxin > 6 EU/ml suggests pneumonia due to Gram-negative bacteria. |
Flanagan, 2001, ** [77] | Mixed ICU, 64 pts | BAL Endotoxin | Clinical & BAL | Sens = 81%, spec = 87%, PPV = 67%, NPV = 95%. |