From: Interventions to prevent iatrogenic anemia: a Laboratory Medicine Best Practices systematic review
Study (year) | Absolute effect (95% CI) | Relative effect | Effect rating | Quality rating | Consistency | Strength of evidence |
---|---|---|---|---|---|---|
Impact on blood loss (mL/day) | ||||||
 MacIsaac (2003) [22] | 11.4a (-19.1, 41.9) | 27% | Moderate | Good | Consistent | Moderate |
 Gleason (1992) [26] | 34.0 (10.1, 57.9) | 49% | Substantial | Fair | ||
 Peruzzi (1993) [25] | 24.0 (7.0, 41.0) | 27% | Moderate | Good | ||
 Widness (2005) [5] | NRb | 24% | Moderate | Good | ||
Impact on hemoglobin decline (g/L/day) | ||||||
 MacIsaac (2003) [22] | -2.2 (-10.4, 6.0)c | -1.2 | Minimal | Good | Inconsistent | Insufficient |
 Mukhopadhyay (2010) [24] | 1.5 (0.6, 2.4) | 32 | Substantial | Fair | ||
 Mukhopadhyay (2011) [23] | 0.3 (0.1, 0.5)d | 6 | Minimal | Fair | ||
 Peruzzi [25] | 1.4 (-0.9, 3.7) | 36 | Substantial | Good | ||
 Rezende [27] | 0.7 (-0.5, 1.2) | 50 | Substantial | Good | ||
 Thorpe [28] | -0.7 (-0.9, -0.4)c | -1 | Minimal | Good | ||
Transfusion risk (≥ 1 transfusion/admission) | ||||||
 MacIsaac [22] | 0.6 (0.3, 0.9) | 75% | Substantial | Good | Inconsistent | Insufficient |
 Mukhopadhyay [24] | 1.4 (0.9, 2.3) | -44% | Substantial | Fair | ||
 Peruzzi [25] | 1.2 (0.7, 2.3) | -17% | Moderate | Good | ||
 Rezende [27] | 0.7 (0.5, 1.2) | 75% | Substantial | Good |