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Fig. 2 | Critical Care

Fig. 2

From: Selective digestive decontamination, a seemingly effective regimen with individual benefit or a flawed concept with population harm?

Fig. 2

Boxplots displaying the median (centre line), IQR (outer limits of box), upper and lower limits (whiskers) and outlier observations (dots) for VAP incidence from groups with > 50% receiving MV where the identified microbe is Pseudomonas (a), Staphylococcus aureus (b), Acinetobacter (c) or Candida species (d) [data from between 113 and 191 studies (catalogued in [24,25,26,27]). The overall benchmark (vertical green line) is the median derived from observational groups (green). Non-AB study is studies of non-antibiotic-based methods of infection prevention; TAP is topical antibiotic prophylaxis. Of note, the benchmark incidence for Pseudomonas VAP here (4.7 per 100 patients) is similar to that in a multi-centre survey [28]. The vertical blue lines are the Pseudomonas VAP incidence observed in ICU’s in Europe (4.8%), the USA (3.4%) and the Asia–pacific regions (3.2%) in the multi-centre survey [28]

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