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Table 1 Patient characteristics

From: Cardiac filling volumes versus pressures for predicting fluid responsiveness after cardiovascular surgery: the role of systolic cardiac function

 

GEF <20% (n= 12)

GEF ≥20% (n= 20)

P-value

Demographic variables

   

Age

66 ± 7

61 ± 7

0.082

Male/female

9/3

16/4

1.000

APACHE II

9 ± 4

9 ± 3

0.690

Coronary artery/major vascular surgery

5/7

13/7

0.2777

CPB yes/no

4/1

9/4

0.648

time of CPB, minute

97 ± 72

78 ± 58

0.564

Echocardiography (LVEF before surgery) good (≥40%)/poor (<40%)

3/9

16/4

1.000

Hemodynamic and respiratory variables

   

HR, b/minute

   

T = 0

75 ± 11

68 ± 12

0.112

T = 90

72 ± 12

72 ± 141

0.101 (for increase)

MAP, mmHg

   

T = 0

85 ± 15

74 ± 12

0.034

T = 90

92 ± 19

84 ± 102

0.608 (for increase)

CVP, mmHg

   

T = 0

5 ± 2

3 ± 2

0.047

T = 30

7 ± 3

5 ± 2

n.a.

T = 60

8 ± 3

6 ± 2

n.a.

T = 90

8 ± 23

7 ± 23

0.813 (for increase)

MPAP, mmHg

   

T = 0

17 ± 6

15 ± 4

0.260

T = 90

2 ± 353

21 ± 43

0.627 (for increase)

PAOP, mmHg

   

T = 0

6 ± 3

7 ± 3

0.477

T = 30

9 ± 2

9 ± 2

n.a.

T = 60

11 ± 3

10 ± 3

n.a.

T = 90

12 ± 23

11 ± 23

0.037 (for increase)

GEDVI, mL/m2

   

T = 0

1,049 ± 247

830 ± 195

0.009

T = 30

1,132 ± 360

840 ± 174

n.a.

T = 60

1,170 ± 387

857 ± 171

n.a.

T = 90

1,220 ± 476

861 ± 189

0.089 (for increase)

SVI, mL/m2

   

T = 0

42 ± 10

52 ± 12

0.022

T = 90

47 ± 94

56 ± 145

0.030 (for increase)

CI, mL/m2

   

T = 0

3.1 ± 0.7

3.4 ± 0.6

0.170

T = 30

3.5 ± 0.7

3.7 ± 0.7

n.a.

T = 60

3.7 ± 0.9

3.9 ± 0.8

n.a.

T = 90

3.9 ± 0.93

3.9 ± 0.63

0.101 (for increase)

GEF, %

   

T = 0

16 ± 4

25 ± 5

n.a.

T = 90

19 ± 3

26 ± 4

n.a.

Distensibility, mL/m2/mmHg

   

T = 0

241 ± 167

229 ± 124

0.830

T = 90

132 ± 641

124 ± 602

0.910 (for decrease)

PEEP, cmH2O

   

T = 0

7.5 ± 2.0

6.7 ± 2.7

0.385

Fluid infused, mL

1,466 ± 296

1,585 ± 291

0.300

Gelatin/HES/albumin

2/3/7

5/8/7

0.436

Fluid balance, mL

1,001 ± 334

1,034 ± 497

0.839

  1. Mean ± SD. APACHE II, Acute Physiology And Chronic Health Evaluation II; CI, cardiac index; CPB, cardiopulmonary bypass; CVP, central venous pressure; GEDVI, global end-diastolic volume index; GEF, global ejection fraction; HES, hydroxyethyl starch; HR, heart rate; LV, left ventricular; LVEF, left ventricular ejection fraction; MAP, mean arterial pressure; MPAP, mean pulmonary artery pressure; PAOP, pulmonary artery occlusion pressure; PEEP, positive end-expiratory pressure. t = 0 and 90 min: prior to and at completion of fluid loading; 1P < 0.05; 2P = 0.001; 3P < 0.001; 4P = 0.017; 5P = 0.007 vs. t = 0; n.a., not applicable.
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Critical Care

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