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  1. The goal of nutrition support is to provide the substrates required to match the bioenergetic needs of the patient and promote the net synthesis of macromolecules required for the preservation of lean mass, or...

    Authors: Christian Stoppe, Sebastian Wendt, Nilesh M. Mehta, Charlene Compher, Jean-Charles Preiser, Daren K. Heyland and Arnold S. Kristof

    Citation: Critical Care 2020 24:499

    Content type: Review

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  2. Post-mortem studies can provide important information for understanding new diseases and small autopsy case series have already reported different findings in COVID-19 patients.

    Authors: Myriam Remmelink, Ricardo De Mendonça, Nicky D’Haene, Sarah De Clercq, Camille Verocq, Laetitia Lebrun, Philomène Lavis, Marie-Lucie Racu, Anne-Laure Trépant, Calliope Maris, Sandrine Rorive, Jean-Christophe Goffard, Olivier De Witte, Lorenzo Peluso, Jean-Louis Vincent, Christine Decaestecker…

    Citation: Critical Care 2020 24:495

    Content type: Research

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  3. Deterioration of lung function during the first week of COVID-19 has been observed when patients remain with insufficient respiratory support. Patient self-inflicted lung injury (P-SILI) is theorized as the re...

    Authors: Pablo Cruces, Jaime Retamal, Daniel E. Hurtado, Benjamín Erranz, Pablo Iturrieta, Carlos González and Franco Díaz

    Citation: Critical Care 2020 24:494

    Content type: Review

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  4. Administration of dexmedetomidine has been reported to improve inflammatory response in animals. We explored the effects of administering dexmedetomidine on the levels of C-reactive protein (CRP) and procalcit...

    Authors: Yoshinori Ohta, Kyohei Miyamoto, Yu Kawazoe, Hitoshi Yamamura and Takeshi Morimoto

    Citation: Critical Care 2020 24:493

    Content type: Research

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  5. Neurotropism of SARS-CoV-2 and its neurological manifestations have now been confirmed. We aimed at describing delirium and neurological symptoms of COVID-19 in ICU patients.

    Authors: Julie Helms, Stéphane Kremer, Hamid Merdji, Malika Schenck, François Severac, Raphaël Clere-Jehl, Antoine Studer, Mirjana Radosavljevic, Christine Kummerlen, Alexandra Monnier, Clotilde Boulay, Samira Fafi-Kremer, Vincent Castelain, Mickaël Ohana, Mathieu Anheim, Francis Schneider…

    Citation: Critical Care 2020 24:491

    Content type: Research

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  6. With recent advances in technology, patients with acute respiratory distress syndrome (ARDS) and severe acute exacerbations of chronic obstructive pulmonary disease (ae-COPD) could benefit from extracorporeal CO2

    Authors: Alain Combes, Georg Auzinger, Gilles Capellier, Damien du Cheyron, Ian Clement, Guglielmo Consales, Wojciech Dabrowski, David De Bels, Francisco Javier González de Molina Ortiz, Antje Gottschalk, Matthias P. Hilty, David Pestaña, Eduardo Sousa, Redmond Tully, Jacques Goldstein and Kai Harenski

    Citation: Critical Care 2020 24:490

    Content type: Research

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  7. High-flow nasal cannula (HFNC) oxygen therapy is being increasingly used to prevent post-extubation hypoxemic respiratory failure and reintubation. However, evidence to support the use of HFNC in chronic obstr...

    Authors: Dingyu Tan, Joseph Harold Walline, Bingyu Ling, Yan Xu, Jiayan Sun, Bingxia Wang, Xueqin Shan, Yunyun Wang, Peng Cao, Qingcheng Zhu, Ping Geng and Jun Xu

    Citation: Critical Care 2020 24:489

    Content type: Research

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  8. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Enrique Guilherme, Matthias Jacquet-Lagrèze, Matteo Pozzi, Felix Achana, Xavier Armoiry and Jean-Luc Fellahi

    Citation: Critical Care 2020 24:487

    Content type: Correction

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    The original article was published in Critical Care 2020 24:442

  9. There is little evidence to support the management of severe COVID-19 patients.

    Authors: Elie Azoulay, Jan de Waele, Ricard Ferrer, Thomas Staudinger, Marta Borkowska, Pedro Povoa, Katerina Iliopoulou, Antonio Artigas, Stefan J. Schaller, Manu Shankar-Hari, Mariangela Pellegrini, Michael Darmon, Jozef Kesecioglu and Maurizio Cecconi

    Citation: Critical Care 2020 24:486

    Content type: Research

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  10. While obesity confers an increased risk of death in the general population, numerous studies have reported an association between obesity and improved survival among critically ill patients. This contrary find...

    Authors: Alexander Decruyenaere, Johan Steen, Kirsten Colpaert, Dominique D. Benoit, Johan Decruyenaere and Stijn Vansteelandt

    Citation: Critical Care 2020 24:485

    Content type: Research

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  11. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Dimitri Titeca-Beauport, Delphine Daubin, Ly Van Vong, Guillaume Belliard, Cédric Bruel, Sami Alaya, Karim Chaoui, Maud Andrieu, Isabelle Rouquette-Vincenti, Frederic Godde, Michel Pascal, Momar Diouf, Christophe Vinsonneau, Kada Klouche and Julien Maizel

    Citation: Critical Care 2020 24:483

    Content type: Correction

    Published on:

    The original article was published in Critical Care 2020 24:280

  12. An amendment to this paper has been published and can be accessed via the original article.

    Authors: June-sung Kim, Hyun-Jin Bae, Chang Hwan Sohn, Sung-Eun Cho, Jeongeun Hwang, Won Young Kim, Namkug Kim and Dong-Woo Seo

    Citation: Critical Care 2020 24:480

    Content type: Correction

    Published on:

    The original article was published in Critical Care 2020 24:305

  13. Besides airway suctioning, patients undergoing invasive mechanical ventilation (iMV) benefit of different combinations of chest physiotherapy techniques, to improve mucus removal. To date, little is known abou...

    Authors: Federico Longhini, Andrea Bruni, Eugenio Garofalo, Chiara Ronco, Andrea Gusmano, Gianmaria Cammarota, Laura Pasin, Pamela Frigerio, Davide Chiumello and Paolo Navalesi

    Citation: Critical Care 2020 24:479

    Content type: Research

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  14. Cardiac surgery–associated acute kidney injury (CSA-AKI) is a major complication that results in increased morbidity and mortality after cardiac surgery. Most established prediction models are limited to the a...

    Authors: Po-Yu Tseng, Yi-Ting Chen, Chuen-Heng Wang, Kuan-Ming Chiu, Yu-Sen Peng, Shih-Ping Hsu, Kang-Lung Chen, Chih-Yu Yang and Oscar Kuang-Sheng Lee

    Citation: Critical Care 2020 24:478

    Content type: Research

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  15. Patients in the intensive care unit (ICU) are known to be at increased risk of developing delirium, but the risk of subsequent neuropsychiatric disorders is unclear. We therefore sought to examine the associat...

    Authors: Kyla N. Brown, Andrea Soo, Peter Faris, Scott B. Patten, Kirsten M. Fiest and Henry T. Stelfox

    Citation: Critical Care 2020 24:476

    Content type: Research

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  16. Pre-hospital circumstances, cardiac arrest characteristics, comorbidities and clinical status on admission are strongly associated with outcome after out-of-hospital cardiac arrest (OHCA). Early prediction of ...

    Authors: Jesper Johnsson, Ola Björnsson, Peder Andersson, Andreas Jakobsson, Tobias Cronberg, Gisela Lilja, Hans Friberg, Christian Hassager, Jesper Kjaergard, Matt Wise, Niklas Nielsen and Attila Frigyesi

    Citation: Critical Care 2020 24:474

    Content type: Research

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  17. Thyroid storm is a life-threatening disease with a mortality rate of over 10%. Although glucocorticoids have been recommended as a treatment option for thyroid storm, supportive evidence based on a large-scale...

    Authors: Atsushi Senda, Akira Endo, Hisateru Tachimori, Kiyohide Fushimi and Yasuhiro Otomo

    Citation: Critical Care 2020 24:470

    Content type: Research

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  18. Cardiac injury is now a common complication of coronavirus disease (COVID-19), but it remains unclear whether cardiac injury-related biomarkers can be independent predictors of mortality and severe disease dev...

    Authors: Xinye Li, Xiandu Pan, Yanda Li, Na An, Yanfen Xing, Fan Yang, Li Tian, Jiahao Sun, Yonghong Gao, Hongcai Shang and Yanwei Xing

    Citation: Critical Care 2020 24:468

    Content type: Research

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  19. The driving pressure of the respiratory system is a valuable indicator of global lung stress during passive mechanical ventilation. Monitoring lung stress in assisted ventilation is indispensable, but achievin...

    Authors: Stella Soundoulounaki, Evangelia Akoumianaki, Eumorfia Kondili, Emmanouil Pediaditis, Georgios Prinianakis, Katerina Vaporidi and Dimitris Georgopoulos

    Citation: Critical Care 2020 24:467

    Content type: Research

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  20. The use of extracorporeal cardiopulmonary resuscitation (ECPR) to restore circulation during cardiac arrest is a time-critical, resource-intensive intervention of unproven efficacy. The current COVID-19 pandem...

    Authors: Elliott Worku, Denzil Gill, Daniel Brodie, Roberto Lorusso, Alain Combes and Kiran Shekar

    Citation: Critical Care 2020 24:462

    Content type: Viewpoint

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  21. Pneumonia is the most common cause of mortality from infectious diseases, the second leading cause of nosocomial infection, and the leading cause of mortality among hospitalized adults. To improve clinical man...

    Authors: Mohammad M. Banoei, Hans J. Vogel, Aalim M. Weljie, Sachin Yende, Derek C. Angus and Brent W. Winston

    Citation: Critical Care 2020 24:461

    Content type: Research

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  22. Chlorhexidine-gluconate (CHG) impregnated dressings may prevent catheter-related bloodstream infections (CRBSI). Chlorhexidine-impregnated sponge dressings (sponge-dress) and gel dressings (gel-dress) have nev...

    Authors: Niccolò Buetti, Stéphane Ruckly, Carole Schwebel, Olivier Mimoz, Bertrand Souweine, Jean-Christophe Lucet and Jean-François Timsit

    Citation: Critical Care 2020 24:458

    Content type: Research

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  23. Nebulised unfractionated heparin (UFH) has a strong scientific and biological rationale and warrants urgent investigation of its therapeutic potential, for COVID-19-induced acute respiratory distress syndrome ...

    Authors: Frank M. P. van Haren, Clive Page, John G. Laffey, Antonio Artigas, Marta Camprubi-Rimblas, Quentin Nunes, Roger Smith, Janis Shute, Mary Carroll, Julia Tree, Miles Carroll, Dave Singh, Tom Wilkinson and Barry Dixon

    Citation: Critical Care 2020 24:454

    Content type: Review

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  24. Hypoxia is common during daily nursing procedures (DNPs) routinely performed on mechanically ventilated patients. The impact of automated ventilation on the incidence and severity of blood oxygen desaturation ...

    Authors: Jonathan Chelly, Sandie Mazerand, Sebastien Jochmans, Claire-Marie Weyer, Franck Pourcine, Olivier Ellrodt, Nathalie Thieulot-Rolin, Jean Serbource-Goguel, Oumar Sy, Ly Van Phach Vong and Mehran Monchi

    Citation: Critical Care 2020 24:453

    Content type: Research

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