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Figure 4 | Critical Care

Figure 4

From: RETRACTED ARTICLE: Diacerhein attenuates the inflammatory response and improves survival in a model of severe sepsis

Figure 4

Effects of diacerhein treatment on insulin signaling in the CLP rat. Representative blots show total protein expression and insulin-induced tyrosine phosphorylation of IRβ, IRS1, and serine phosphorylation of Akt in liver (A), adipose tissue (B), and muscle (C) of sham and septic rats. Data are presented as mean ± SEM from six to eight rats per group. *P < 0.05 versus Sham/Vehicle; #P < 0.05 (Sepsis/Veh versus Sepsis/Dia). IB, immunoblot; Sham, Sham/Vehicle; Sham+Dia, Sham/Diacerhein; Sepsis, Sepsis/Vehicle; Sepsis+Dia: Sepsis/Diacerhein.

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