Risk stratification and prognostic performance of the predisposition, infection, response, and organ dysfunction (PIRO) scoring system in septic patients in the emergency department: a cohort study

Table 3 Predictive ability of the four components of the PIRO system

Outcome variable	Predictor	B	SE	Wald	P value	OR	95% CI for OR
							5%	95%
ICU admission	Predisposition	0.387	0.140	7.591	0.006	1.472	1.118	1.939
	Infection	0.440	0.210	4.382	0.036	1.553	1.028	2.344
	Response	0.364	0.093	15.351	0.000	1.439	1.200	1.727
	Organ dysfunction	0.665	0.058	132.428	0.000	1.944	1.736	2.177
	Constant	−7.743	1.031	56.440	0.000	0.000
MOD	Predisposition	0.409	0.110	13.872	0.000	1.506	1.214	1.867
	Infection	0.378	0.166	5.228	0.022	1.460	1.056	2.020
	Response	−0.125	0.073	2.907	0.088	0.883	0.764	1.019
	Organ dysfunction	0.544	0.044	154.852	0.000	1.723	1.582	1.878
	Constant	−4.272	0.727	34.553	0.000	0.014
28-day mortality	Predisposition	0.225	0.112	4.060	0.044	1.253	1.006	1.560
	Infection	−0.017	0.144	0.014	0.904	0.983	0.741	1.303
	Response	−0.331	0.073	20.345	0.000	0.718	0.622	0.829
	Organ dysfunction	0.410	0.037	125.453	0.000	1.507	1.403	1.620
	Constant	−1.906	0.591	10.391	0.001	0.149

CI, confidence interval; MOD, multiple organ dysfunction; OR, odds ratio; PIRO, predisposition, infection, response, and organ dysfunction; SE, standard error.

ISSN: 1364-8535