Risk stratification and prognostic performance of the predisposition, infection, response, and organ dysfunction (PIRO) scoring system in septic patients in the emergency department: a cohort study

Table 5 The independent predictors of outcomes

Outcome variable	Independent predictor	B	SE	Wald	P value	OR	95% CI
							5%	95%
ICU admission	PIRO	0.564	0.061	84.853	0.000	1.758	1.559	1.982
	MEDS	−0.020	0.033	0.393	0.531	0.980	0.919	1.044
	APACHE II	0.045	0.022	4.233	0.040	1.046	1.002	1.092
	Constant	−9.292	0.744	155.773	0.000	0.000
MOD	PIRO	0.295	0.041	53.053	0.000	1.343	1.241	1.454
	MEDS	0.042	0.026	2.747	0.097	1.043	0.992	1.097
	APACHE II	0.065	0.017	14.260	0.000	1.067	1.032	1.104
	Constant	−5.920	0.468	160.023	0.000	0.003
28-day mortality	PIRO	0.112	0.036	9.843	0.002	1.119	1.043	1.200
	MEDS	0.065	0.026	6.481	0.011	1.067	1.015	1.122
	APACHE II	0.075	0.017	20.207	0.000	1.078	1.043	1.114
	Constant	−4.628	.395	137.245	0.000	0.010

APACHE, Acute Physiology and Chronic Health Evaluation; CI, confidence interval; MEDS, Mortality in Emergency Department Sepsis; MOD, multiple organ dysfunction; OR, odds ratio; PIRO, predisposition, infection, response, and organ dysfunction; SE, standard error.

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