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Table 2 1999 National projections of severe sepsis by tumor types, adultsa only

From: Hospitalized cancer patients with severe sepsis: analysis of incidence, mortality, and associated costs of care

Tumor type

Hospitalizationsb

No severe sepsis mortality

Severe sepsis cases

Severe sepsis mortality

Severe sepsis ratec

Relative risk of severe sepsisd(confidence interval)

Noncancer

      

   Total patientse

22,651,429

2.0

790,743

24.9

4.2

1.00

Cancer

      

   Total patientse

2,531,994

7.1

126,209

37.8

16.4

3.96 (3.94 – 3.99)

Hematologic tumor

      

   Non-Hodgkins lymphoma

159,984

5.9

11,729

40.4

43.4

10.26 (10.08–10.44)

   Lymphocytic leukemia

60,365

5.9

6447

32.8

77.8

18.40 (17.97–18.84)

   Hodgkin's disease

20,617

3.3

1,575

38.0

17.2

4.07 (3.87–4.27)

   Multiple myeloma

69,576

6.1

6588

32.2

142.2

33.61 (32.87–34.38)

   Myeloid leukemia

53,523

9.7

8234

35.2

275.5

65.15 (63.95–66.36)

   Monocytic leukemia

949

14.5

110

45.8

108.3

25.62 (21.5–30.6)

   Total hematologic tumor

365,014

6.3

34,684

36.1

66.4

15.71 (15.55–15.88)

Solid tumors

      

   Breast cancer

197,808

3.1

2915

34.6

1.6

0.39 (0.38–0.4)

   Prostate cancer

225,789

3.5

6883

27.5

4.8

1.13 (1.1–1.16)

   Colon and rectum cancer

232,423

5.1

9409

35.8

9.8

2.32 (2.27–2.37)

   Urinary bladder cancer

85,256

3.6

3176

27.8

7.1

1.67 (1.61–1.73)

   Skin melanoma

14,203

4.9

200

38.1

0.5

0.11 (0.1–0.13)

   Corpus and uterus cancer

51,212

2.2

1002

27.1

2.4

0.57 (0.53–0.6)

   Lung and bronchus cancer

359,236

12.0

20,377

45.2

58.2

13.76 (13.58–13.95)

   Thyroid cancer

27,467

1.1

178

32.4

0.9

0.21 (0.18–0.24)

   Kidney and renal pelvis cancer

45,656

4.8

1510

28.0

8.8

2.07 (1.97–2.18)

   Ovary cancer

57,315

5.1

1682

33.3

10.8

2.56 (2.44–2.68)

   Brain and other nervous cancer

43,096

6.0

1512

28.2

27.5

6.50 (6.18–6.83)

   Total solid tumors

1,339,463

6.1

48,846

37.2

7.6

1.81 (1.79–1.82)

  1. aAdults defined as aged > 20 years. bAfter adjusting for age and gender, cancer patients are much more likely to be hospitalized (relative risk, 2.77; 95% confidence interval, 2.773–2.779) and to be hospitalized with severe sepsis (relative risk, 3.96; 95% confidence interval, 3.94–3.99). cSevere sepsis cases per 1000 population. dRelative risk of severe sepsis between tumor type and noncancer population (excluding childbirth). eChildbirth-related discharges not included.