Table 1 In vitro antifungal susceptibility of Candida species isolated from ICU-acquired candidaemia episodes
From: Determinants of mortality in non-neutropenic ICU patients with candidaemia
Agent | MIC* | Candida albicans (n = 106) | Candida glabrata (n = 32) | Candida krusei (n = 7) | Candida parapsilosis (n = 14) | Candida tropicalis (n = 10) |
|---|---|---|---|---|---|---|
AMB | MIC50 | 0.125 | 0.25 | 0.25 | 0.5 | 0.5 |
MIC90 | 0.25 | 0.5 | 0.5 | 0.5 | 0.5 | |
5FC | MIC50 | 0.125 | 0.03 | 8 | 0.125 | 0.06 |
MIC90 | 0.5 | 0.03 | 16 | 0.25 | 0.125 | |
FLU | MIC50 | 1 | 32 | 64 | 2 | 1 |
MIC90 | 2 | 64 | >64 | 4 | 4 | |
ITR | MIC50 | 0.06 | 2 | 0.5 | 0.25 | 0.25 |
MIC90 | 0.125 | 16 | 0.5 | 0.5 | 0.5 | |
VOR | MIC50 | 0.016 | 0.5 | 0.5 | 0.06 | 0.06 |
MIC90 | 0.03 | 1 | 0.5 | 0.25 | 0.5 | |
POS | MIC range (no. tested) | 0.008 to 0.06 (16) | 0.03 to 8 (7) | 0.125 (1) | - | 0.008 to 0.06 (4) |
CAS | MIC range (no. tested) | 0.03 to 0.25 (27) | 0.06 to 0.25 (11) | 0.25 to 1 (3) | 0.125 (1) | 0.06 to 0.5 (7) |