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Table 1 Incidence of post-extubation stridor and laryngeal edema

From: Clinical review: Post-extubation laryngeal edema and extubation failure in critically ill adult patients

Study

Year

Extubations or participants (n)

Cases (n)

%

Definition

Post-extubation stridor

     

   Epstein and colleagues [1]

1998

74

11

15

Stridor with resolution upon reintubation

   Maury and colleagues [25]

2004

115

4

3.5

High-pitched inspiratory wheeze within 24 hours of extubation with respiratory rate >30/minute

   Sandhu and colleagues [26]

2000

110

13

11.8

High-pitched inspiratory wheeze requiring medical intervention

   Miller and Cole [27]

1996

100

6

6

High-pitched inspiratory wheeze requiring medical intervention

   Kriner and colleagues [8]

2005

462

20

4.3

Inspiratory grunting, whistling or wheezing requiring medical intervention within 24 hours after extubation

   Ding and colleagues [28]

2006

51

4

7.8

High-pitched inspiratory wheeze associated with respiratory distress

   Colice and colleagues [2]

1989

82

5

6

Post-extubation stridor or hoarseness

   Ho and colleagues [7]

1996

38a

10

26

Crowing sound on inspiration

   Jaber and colleagues [30]

2003

112

13

12

High-pitched inspiratory wheeze requiring medical intervention

   Cheng and colleagues [3]

2006

43

13

30.2

High-pitched inspiratory wheeze requiring medical intervention (in control group of intervention arm with positive cuff leak test)

   de Bast and colleagues [36]

2002

76

10

13

Inspiratory wheezing

   Lee and colleagues [13]

2007

40

11

27.5

Stridor heard with stethoscope

Laryngeal edema

     

   Francois and colleagues [6]

2007

343a

76

22

Stridor with respiratory distress with need for medical intervention (minor) or severe respiratory distress needing reintubation <24 hours after extubation (major)

   Darmon and colleagues [4]

1992

663

28

4.2

Laryngeal dyspnea and/or stridor (minor laryngeal edema) or the need for reintubation due to laryngeal edema as confirmed by endoscopy (major laryngeal edema)

   de Bast and colleagues [36]

2002

76

8

11

Stridor with respiratory distress requiring reintubation within 24 hours, confirmed by fiberoptic examination or direct view

   Chung and colleagues [55]

2006

95

35

36.8

Near total occlusion of the airway as seen on video bronchoscopy

  1. aPlacebo group.