Infections of respiratory or abdominal origin in ICU patients: what are the differences?

Table 5 Organ dysfunction patterns

Characteristic	All patients (n = 542)	Abdominal infection (n = 162)	Respiratory infection (n = 380)	P-value
Sepsis syndromes at any time during the ICU stay
Severe sepsis	449 (82.8%)	128 (79.0%)	321 (84.5%)	0.12
Septic shock	241 (44.5%)	81 (50.0%)	160 (42.1%)	0.09
Procedures during ICU stay
Mechanical ventilation	437 (80.6%)	129 (79.6%)	308 (81.1%)	0.70
Hemofiltration	69 (12.7%)	29 (17.9%)	40 (10.5%)	0.02
Hemodialysis	27 (5.0%)	8 (4.9%)	19 (5.0%)	0.97
SOFA scores
SOFA max	8.4 ± 4.4	8.4 ± 4.8	8.4 ± 4.3	0.90
SOFA mean	5.6 ± 3.9	5.6 ± 4.0	5.6 ± 3.9	0.95
Early organ failure^a
Renal	174 (32.1%)	62 (38.3%)	112 (29.5%)	0.04
Respiratory	286 (52.8%)	79 (48.8%)	207 (54.5%)	0.22
Coagulation	64 (11.8%)	28 (17.3%)	36 (9.5%)	0.01
Hepatic	33 (6.1%)	7 (4.3%)	26 (6.8%)	0.26
CNS	132 (24.4%)	16 (9.9%)	116 (30.5%)	< 0.001
Cardiovascular	249 (45.9%)	90 (55.6%)	159 (41.8%)	0.003
Late organ failure^b
Renal	74 (13.7%)	16 (9.9%)	58 (15.3%)	0.09
Respiratory	56 (10.3%)	17 (10.5%)	39 (10.3%)	0.93
Coagulation	16 (3.0%)	7 (4.3%)	9 (2.4%)	0.21
Hepatic	16 (3.0%)	8 (4.9%)	8 (2.1%)	0.07
CNS	27 (5.0%)	8 (4.9%)	19 (5.0%)	0.97
Cardiovascular	30 (5.5%)	6 (3.7%)	24 (6.3%)	0.22
Organ failure any time
Renal	248 (45.8%)	78 (48.1%)	170 (44.7%)	0.46
Respiratory	342 (63.1%)	96 (59.3%)	246 (64.7%)	0.22
Coagulation	80 (14.8%)	35 (21.6%)	45 (11.8%)	0.003
Hepatic	49 (9.0%)	15 (9.3%)	34 (8.9%)	0.90
CNS	159 (29.3%)	24 (14.8%)	135 (35.5%)	< 0.001
Cardiovascular	279 (51.5%)	96 (59.3%)	183 (48.2%)	0.01

CNS: Central nervous system; ^a, occurring within 48 hours of a diagnosis of sepsis;
^b, occurring more than 48 hours after a diagnosis of sepsis

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