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Figure 2 | Critical Care

Figure 2

From: Acute pancreatitis with organ dysfunction associates with abnormal blood lymphocyte signaling: controlled laboratory study

Figure 2

The effects of infliximab and anakinra on bacteria-induced NF-κB phosphorylation in lymphocytes. Whole blood samples of healthy subjects were left without cytokine inhibitor or mixed with infliximab, an anti-TNF mAb, anakinra, an IL-1 receptor antagonist, or both, and then left without further supplement or supplemented with E. coli, S. aureus, or S. epidermidis. *P < 0.05 (N = 4 to 6). + Significantly different (P < 0.05) from respective E. coli, S. aureus, and S. epidermidis groups with the exception of S. epidermidis with infliximab only (P = 0.055), or infliximab + anakinra (P = 0.054).

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