From: Clinical neurophysiological assessment of sepsis-associated brain dysfunction: a systematic review
 | Ref | Type of quantitative analysis | Findings | Diagnostic and prognostic value of the abnormalities |
---|---|---|---|---|
Case-control study (patients with systemic infection versus controls) | ||||
 | 16 | Spectral analysis (Fast Fourier Transform) | Lower relative power in the alpha band; higher relative power in the theta and beta band; lower alpha peak frequency; higher theta peak frequency | NA |
Case series of patients with sepsis | ||||
 | 19 | Spectral analysis (Fast Fourier Transform); nonlinear analysis (Kaplan z-score) | Lower spectral EEG ratio; higher Kaplan z-score | Kaplan z-score correlated negatively with the APACHE II score. |
Case series or case-control study that included patients with and without sepsis | ||||
 | 26 | Burst suppression index (provided from a BIS monitor) | Burst suppression occurred in 49 of 125 patients (39%) | Diagnostic value of the presence of burst and suppression for sepsis (Sen = 0.42; Spe = 0.66; PLR = 1.2; NLR = 0.9). Burst suppression with higher six-month mortality (hazard ratio = 2.04, P = 0.02). |