Table 3 Baseline characteristics and hospital course of community-acquired sepsis events (identified by manual chart review) and sepsis events identified by Martin and colleagues’ discharge diagnoses
From: Discharge diagnoses versus medical record review in the identification of community-acquired sepsis
Characteristic | Community-acquired sepsis (column %) ( n = 156) | Martin-sepsis (column%) ( n = 55) | Discordances favoring community-acquired sepsis (column %) ( n = 113) | Discordances favoring Martin-sepsis (column %) ( n = 12) | Pvalue Community-acquired versus Martin-sepsis discordancesa |
|---|---|---|---|---|---|
Mean age (SD) | 69.7 (9.1) | 70.6 (8.8) | 69.3 (9.3) | 70.3 (10.3) | 0.72 |
Sex | |||||
Male | 58.3 | 67.3 | 54.9 | 66.7 | 0.43 |
Female | 41.7 | 32.7 | 45.1 | 33.3 | |
Race | |||||
White | 64.7 | 58.2 | 68.1 | 33.3 | 0.92 |
Black | 35.3 | 41.8 | 31.9 | 66.7 | |
Income | |||||
< $20,000 | 25.6 | 27.3 | 25.7 | 33.3 | 0.70 |
$20,000 to 34,000 | 37.2 | 41.8 | 34.5 | 33.3 | |
$35,000 to 74,000 | 21.8 | 21.8 | 21.2 | 16.7 | |
≥ $75,000 | 9.6 | 1.8 | 12.4 | 0.0 | |
Unknown | 5.8 | 7.3 | 6.2 | 16.7 | |
Education | |||||
Less than high school | 22.4 | 21.8 | 21.2 | 8.3 | 0.70 |
High school graduate | 31.4 | 30.9 | 32.7 | 41.7 | |
Some college | 28.2 | 27.3 | 29.2 | 33.3 | |
College or higher | 18.0 | 20.0 | 16.7 | 16.7 | |
Health behaviors | |||||
Tobacco use | |||||
Never | 32.3 | 34.6 | 32.1 | 41.7 | 0.79 |
Past | 52.3 | 52.7 | 50.9 | 41.7 | |
Current | 15.5 | 12.7 | 17.0 | 16.7 | |
Alcohol use | |||||
None | 67.7 | 67.3 | 69.6 | 83.3 | 0.36 |
Moderate | 29.0 | 29.1 | 27.7 | 16.7 | |
Heavy | 3.2 | 3.6 | 2.7 | 0.0 | |
Chronic medical conditions | |||||
Atrial fibrillation | 15.6 | 17.3 | 17.8 | 50.0 | 0.03 |
Cancer | 19.5 | 22.2 | 19.0 | 27.3 | 0.53 |
Chronic kidney disease | 26.9 | 27.3 | 25.7 | 16.7 | 0.48 |
Chronic lung disease | 18.0 | 7.3 | 22.1 | 8.3 | 0.22 |
Coronary artery disease | 29.6 | 24.5 | 33.3 | 41.7 | 0.57 |
Deep vein thrombosis | 12.9 | 16.4 | 11.6 | 16.7 | 0.62 |
Diabetes | 35.3 | 47.3 | 34.5 | 83.3 | <0.001 |
Dyslipidemia | 66.7 | 70.0 | 64.2 | 55.6 | 0.61 |
Hypertension | 70.3 | 35.5 | 71.4 | 58.3 | 0.36 |
Myocardial infarction | 18.3 | 20.8 | 18.8 | 33.3 | 0.26 |
Obesity (abnormal BMI or WC) | 62.8 | 63.6 | 61.1 | 50.0 | 0.46 |
Peripheral artery disease | 3.9 | 5.5 | 3.54 | 8.33 | 0.47 |
Stroke | 19.4 | 25.5 | 18.8 | 41.7 | 0.09 |
Infection type | |||||
Lung | 51.3 | 29.1 | 57.5 | 8.3 | <0.001 |
Kidney | 17.3 | 27.3 | 13.3 | 25.0 | |
Abdominal | 14.7 | 3.6 | 19.5 | 8.3 | |
Skin | 6.4 | 10.9 | 5.3 | 16.7 | |
Other | 10.3 | 29.1 | 4.4 | 41.7 | |
28-hour SOFA score | 2 (1 to 3) | 2 (1 to 3) | 1 (0 to 3) | 2 (1 to 3) | 0.56 |
Median (IQR) MEDS score | 9 (6 to 13) | 11 (6 to 13) | 9 (6 to 11) | 9 (6 to 10.5) | 0.12 |
Admission to ICU | 13.5 | 23.6 | 8.0 | 8.3 | 0.96 |
Hospital mortality | 10.3 | 25.5 | 5.3 | 33.3 | 0.006 |