Influence of temperature on thromboelastometry and platelet aggregation in cardiac arrest patients undergoing targeted temperature management

Table 5 The difference in Multiplate®Analyzer measurements performed at 33 °C and 37 °C in 40 cardiac arrest patients

	Hypothermia (body core temp median 33.1 °C), n = 39 33 °C versus 37 °C		Normothermia (body core temp median 37.5 °C), n = 37 33 °C versus 37 °C
	Multiplate®Analyzer, (AU*min)		Multiplate®Analyzer, (AU*min)
	Mean difference (95 % CI)	P value	Mean difference (95 % CI)	P value
COLtest®^a	–4 (–30; 23)	0.79	–62.0 (–87; –37)	<0.001
TRAPtest®	–38 (–96; 20)	0.19	–12.5 (–84; 59)	0.73
ASPItest®
All^a	–24 (–83; 35)	0.43	–106 (–158; –53)	<0.001
No aspirin (n = 9)	–71 (–199; 57)	0.28	–176 (–336; –16)	0.03
Aspirin (n = 26)	–27 (–53; –1)	0.04	–76 (–108; –45)	<0.001
ADPtest®
No ADP inhibitors (n = 20)	106 (68; 144)	<0.001	51 (18; 83)	0.003
ADP inhibitors (n = 18)	38 (6; 69)	0.02	2 (–33; 37)	0.92

temp temperature, n number, CI confidence interval, ADP inhibitors adenosine diphosphate receptor inhibitors, AU*min (y-axis is expressed in Aggregation units (AU) and x-axis in minutes). ^aThe body core temperature significantly affected the differences in results at 33 °C and 37 °C

ISSN: 1364-8535