Table 3 Multivariable analysis of association between splicing factors variants and acute respiratory distress syndrome

  CELF2: rs3814634 (GT/GG vs TT)

2.95

1.10–8.06

0.032

  CELF2: rs7068124 (CT/TT vs CC)

4.28

1.58–11.64

0.004

  CELF2: rs10905928 (AC/AA vs CC)

2.66

1.03–6.89

0.044

  TIA1: rs2592178 (AG/AA vs GG)

3.70

1.49–9.15

0.005

  TIA1: rs13402990 (AT vs AA)

5.42

1.34–21.9

0.018

 High risk (TG)_mT_n alleles^a

3.01

1.27–7.14

0.012

 Age group (≥11 years)

14.9

5.53–40.1

<0.0001

 Asthma

0.55

0.15–2.00

0.36

  CELF2: rs2277212 (TT vs AA/AT)

3.22

1.26–8.33

0.014

 Age group (≥11 years)

9.20

3.93–21.6

<0.0001

 Asthma

0.20

0.04–0.96

0.04