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Fig. 7 | Critical Care

Fig. 7

From: Exosomes from endothelial progenitor cells improve outcomes of the lipopolysaccharide-induced acute lung injury

Fig. 7

miRNA-126-3p and miRNA-126-5p regulate the expression levels of cell tight junction proteins in LPS-stimulated SAECs. SAECs were transfected with either miR-126-3p mimic, miR-126-5p mimic, or control miRNA for 48 h and stimulated with LPS (100 ng/ml) for 24 h. mRNA levels of claudin1 (a, d), claudin4 (b, e), and occludin (c) in SAECs were measured by RT-qPCR. GAPDH served as an internal control. *p < 0.05 compared with the control group; #p < 0.05 compared with the LPS group. The experiments were performed at least three independent times. Results are represented as mean ± SE

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