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Table 2 SAEC genes regulated by miR-126-5p with relevance to the lung barrier integrity and inflammation by RNA sequencing analysis

From: Exosomes from endothelial progenitor cells improve outcomes of the lipopolysaccharide-induced acute lung injury

Category

Gene

Fold change

p value

Epithelial tight junction

Claudin1

1.8 ± 0.03

1.65 × 10−11

Claudin4

2.2 ± 0.12

1.56 × 10−10

Vascular permeability factor

VEGFα

0.28 ± 0.01

8.34 × 10−28

Inflammatory alarmin

HMGB1

0.66 ± 0.02

2.01 × 10−7

  1. Only selected relevant genes were listed here; the other genes altered by miR-126-5p were list in Additional file 2
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Critical Care

ISSN: 1364-8535