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Table 1 (abstract P366). Measurements in sodium thiosulfate (STS) and placebo-treated swine at baseline, at the end of 3h of hemorrhagic shock (HS), and during resuscitation from HS (24, 48, and 72h)

From: 39th International Symposium on Intensive Care and Emergency Medicine

Parameter

Treatment

Baseline

Schock

72h

pH

Placebo

7.46 (7.45; 7.49)

7.30 (7.25; 7.41)*

7.51 (7.48; 7.55)

Thiosulfate

7.45 (7.42; 7.47)

7.26 (7.24; 7.38)*

7.52 (7.52; 7.55)

Base excess

(mmol·L-1)

Placebo

3.6 (2.5; 6.0)

-2.6 (-5.4; 1.8)

8.7 (7.8; 10.7)*

Thiosulfate

4.9 (0.9; 5.4)

-3.5 (-8.2; -0.1)*

9.4 (7.9; 10.0)*

Lactate

(mmol·L-1)

Placebo

3.1 (2.4; 3.8)

6.0 (4.5; 8.0)

0.8 (0.7; 1.2)*

Thiosulfate

2.4 (2.3; 3.8)

7.5 (5.8; 8.8)*

0.8 (0.6; 1.1)

  1. *P<0.05 vs. baseline in the same treatment group. Pplat=plateau pressure. Data is presented as median and interquartile range