Table 1 (abstract P078). impact of factors likely to influence PK/PD parameters on target achievement
From: 39th International Symposium on Intensive Care and Emergency Medicine
| Â | Â | C<4MIC | C>4MIC | p value |
|---|---|---|---|---|
Administration method | intermittent/extended/continuous | 0/0/8 | 1/1/2 | 0.333 |
Dosing | Standard dose / Adjusted Body Weight /other | 5/2/1 | 1/1/2 | 1 |
Loading dose | Â | 4 | 4 | 0.208 |
SOFA at TZP initiation | Median [Q1; Q3] | 7 [5;8] (n=8) | 11.5 [8;14] (n=4) | 0.039 |
SOFA at sepsis peak | Median [Q1; Q3] | 7.5 [5;9] (n=8) | 12 [11;15] (n=3) | 0.031 |
Albumin (g/L) | Median [Q1; Q3] | 23.7 [20.6; 25.2] (n=6) | 21 [18.4; 33] (n=3) | 0.905 |
Renal clearance (ml/min) | Median [Q1; Q3] | 45.2 [39; 100](n=5) | 13.05 (n=1) | - |