Skip to main content

Table 1 Baseline characteristics of the patients recorded at admission to the ICU

From: Nuclear magnetic resonance-based serum metabolomic analysis reveals different disease evolution profiles between septic shock survivors and non-survivors

 

Total/average

Survivors

Non-survivors

Adj P

FDR

Number of patients

70

40

30

  

Male (%)

40 (57%)

27 (67%)

13 (32%)

0.07

0.09

Age

70.1 ± 0.16

68.5 ± 0.29

72.1 ± 0.36

0.12

0.23

Temperature (°C)

37.3 ± 0.02

37.1 ± 0.03

36.9 ± 0.05

0.32

0.35

Mean arterial pressure (mmHg) at admission

72.8 ± 2,44

71,0 ± 3,25

75.2 ± 3.72

0.41

0.35

pH at admission

7.3 ± 0.00

7.31 ± 0.00

7.29 ± 0.00

0.43

0.53

PaO2 (mmHg)H0

144.7 ± 1.54

167.5 ± 2.83

113.6 ± 3.12

0.05

0.13

PaCO2 (mmHg)

37.6 ± 0.18

37.6 ± 0.31

37.5 ± 0.45

0.66

0.63

PaO2/FiO2 ratioH0

212.5 ± 4.10

168.6 ± 3.19

242.2 ± 5.59

0.04

0.07

Lactate (mmol/L)H0

5.0 ± 0.07

3.7 ± 0.11

6.6 ± 0.17

0.01

0.03

Creatininemia (μmol/L)H0

212.2 ± 3.88

200.1 ± 4.34

241.9 ± 3.55

0.07

0.15

Glycemia (mmol/L)

9.8 ± 0.09

9.9 ± 0.20

9.6 ± 0.23

0.91

0.95

Hemoglobin (mmol/L)

10.5 ± 0.03

10.1 ± 0.06

10.9 ± 0.07

0.09

0.06

Albumin (g/L)

24.6 ± 0.13

22.2 ± 0.15

26.8 ± 0.38

0.11

0.21

Platelet (g/L)

156.7 ± 1.53

151.8 ± 2.61

162.2 ± 3.70

0.33

0.13

Total bilirubin (μmol/L)

38.4 ± 0.90

37.8 ± 1.90

39.1 ± 1.53

0.54

0.77

CRP (mg/dL)

162.3 ± 2.15

174.0 ± 3.98

147.4 ± 4.71

0.49

0.67

PCT (mg/dL)

25.2 ± 0.52

28.0 ± 1.15

21.6 ± 1.39

0.74

0.88

SAPSII

59.0 ± 0.24

55.2 ± 0.39

64.3 ± 0.58

0.02

0.07

SOFAH0

11.7 ± 0.06

10.9 ± 0.11

12.4 ± 0.12

0.10

0.15

SOFAH24

9.4 ± 0.06

8.7 ± 0.11

10.3 ± 0.10

0.07

0.11

ICU LOS (day)

9.16 ± 1.21

15.1 ± 1.36

3.62 ± 0.09

0.05

0.09

Mechanical ventilation (%)

84%

75%

93%

  

Hospital-acquired infection (%)

45%

35%

60%

  

Sepsis causes (%)

 Pulmonary

54%

55%

53%

  

 Abdominal

30%

22%

40%

  

 Urinary tract

7%

7%

6%

  

 Others

8%

15%

0%

  
  1. All the data is represented as mean ± standard error of mean (SEM)
  2. PaO2 partial pressure of arterial oxygen, FiO2 percentage of inspired oxygen, SOFA Sepsis-related Organ Failure Assessment, SOFAH0 SOFA measured at H0, SOFAH24 SOFA measured at H24, SAPSII new simplified acute physiology score, LOS length of stay, FDR false discovery rate, Adj P P value adjusted with Bonferroni correction