From: Prone positioning under VV-ECMO in SARS-CoV-2-induced acute respiratory distress syndrome
Variables | Before prone position | After prone position | P value |
---|---|---|---|
Mechanical ventilation settings | |||
Tidal volume (mL/kg) | 2.4 (1.8–2.9) | 2.4 (1.8–2.7) | 0.42 |
RR (breaths/min) | 20 (16–25) | 19 (16–25) | 0.87 |
Plateau airway pressure (cmH2O) | 28 (26–32) | 29 (28–32) | 0.43 |
PEEP (cmH2O) | 14 (12–18) | 16 (12–20) | 0.36 |
Respiratory system compliance (mL/cmH2O) | 18.6 (13.7–25.9) | 17.9 (12.8–26.5) | 0.92 |
Driving pressure (cmH2O) | 14.5 (12–16.5) | 14.5 (11–16) | 0.56 |
Inspired fraction of oxygen (%) | 70 (60–100) | 67.5 (52.5–95) | 0.16 |
ECMO settings | |||
ECMO blood flow (L/min) | 6.2 (6–6.7) | 6 (5.8–6.7) | 0.41 |
Sweep gas flow (L/min) | 7 (6–8.5) | 7 (6.8–9) | 0.15 |
FDO2 (%) | 100 (80–100) | 100 (80–100) | 0.56 |
Gas analysis | |||
PaO2 (mmHg) | 64 (51–78) | 82 (66–109) | 0.007 |
PaO2/FiO2 (mmHg) | 84 (73–108) | 112 (83–157) | 0.002 |
PaCO2 (mmHg) | 44 (41–46) | 42 (36–49) | 0.27 |
pH | 7.38 (7.35–7.43) | 7.38 (7.34–7.42) | 0.47 |