Table 1 Characteristics of 30 patients with acute respiratory distress syndrome induced or not by coronavirus disease-19
C-ARDS (n = 17) | NC-ARDS (n = 13) | p value | |
|---|---|---|---|
Patients' characteristics | |||
Age (years) | 54 [50, 67] | 69 [53, 71] | 0.15 |
Male, n (%) | 16/17 (94%) | 11/13 (85%) | 0.56 |
Weight (kg) | 90 [80, 106] | 80 [66, 90] | 0.07 |
Body mass index, kg/m2 | 30.2 [27.8, 33.2] | 28.7 [24.8, 31.1] | 0.16 |
History of COPD, n (%) | 1/17 (6%) | 1/13 (8%) | > 0.99 |
History of chronic heart failure, n (%) | 3/17 (18%) | 4/13 (31%) | 0.67 |
History of chronic kidney failure, n (%) | 3/17 (18%) | 3/13 (23%) | > 0.99 |
Immunosuppression, n (%) | 1/17 (6%) | 2/13 (15%) | 0.56 |
Time from first symptoms to intubation (days) | 9 [6.5, 10] | NA | |
SAPS 2 | 34 [27, 38] | 62 [42, 83] | 0.01 |
PaO2/FiO2 at intubation (mmHg) | 98 [90, 144] | 135 [80, 182] | 0.64 |
CT scan and echocardiography | |||
Presence of lung consolidation on CT scan, n (%) | 2/11 (18%) | 4/5 (80%) | 0.04 |
Pulmonary embolism on CT angiography, n (%) | 3/8 (38%) | 1/5 (20%) | > 0.99 |
Acute cor pulmonale on echocardiography, n (%) | 8/17 (47%) | 1/13 (8%) | 0.04 |
Patent foramen ovale, n (%) | 1/17 (6%) | 0 | > 0.99 |
Outcomes | |||
Need for vasopressor, n (%) | 11/17 (65%) | 11/13 (85%) | 0.41 |
ECMO upon ICU stay, n (%) | 2/17 (12%) | 1/13 (8%) | > 0.99 |
Tracheotomy during ICU stay, n (%) | 3/17 (18%) | 0 | 0.24 |
Duration of mechanical ventilation (days) | 13 [9, 29] | 13 [8, 22] | 0.53 |
Duration of ICU stay (days) | 18 [12, 30] | 17 [11, 22] | 0.75 |
Death in ICU, n (%) | 4/17 (24%) | 6 /13 (46%) | 0.26 |