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Table 2 Patient characteristics during ICU stay according to disease groups and 28-day mortality

From: Relationship between ventilator-associated pneumonia and mortality in COVID-19 patients: a planned ancillary analysis of the coVAPid cohort

 

SARS-CoV-2 pneumonia

Influenza pneumonia

No viral infection

Alive (n = 402)

Dead (n = 166)

Alive (n = 350)

Dead (n = 132)

Alive (n = 344)

Dead (n = 182)

Antiviral treatment

226/401 (56.4)

96/165 (58.2)

319/349 (91.4)

118/132 (89.4)

19/343 (5.5)

5/180 (2.8)

 Oseltamivir

30/399 (7.5)

14/164 (8.5)

314/344 (91.3)

116/131 (88.5)

18/342 (5.3)

4/179 (2.2)

 Remdesivir

21/399 (5.3)

6/164 (3.7)

0/344 (0.0)

0/131 (0.0)

0/342 (0.0)

0/179 (0.0)

 Lopinavir-Ritonavir

96/399 (24.1)

51/164 (31.1)

0/344 (0.0)

0/131 (0.0)

0/342 (0.0)

0/179 (0.0)

 Lopinavir-Ritonavir + interferon

12/399 (3.0)

9/164 (5.5)

0/344 (0.0)

0/131 (0.0)

0/342 (0.0)

0/179 (0.0)

 Hydroxychloroquine

134/399 (33.6)

39/164 (23.8)

0/344 (0.0)

1/131 (0.8)

0/342 (0.0)

0/179 (0.0)

Corticosteroids

131/380 (34.5)

71/162 (43.8)

124/345 (35.9)

58/130 (44.6)

97/343 (28.3)

64/182 (35.2)

 Hydrocortisone

27/377 (7.2)

32/160 (20.0)

64/343 (18.7)

43/130 (33.1)

39/340 (11.5)

41/180 (22.8)

 Dexamethasone

32/377 (8.5)

16/160 (10.0)

1/343 (0.3)

0/130 (0.0)

6/340 (1.8)

4/180 (2.2)

 Methylprednisolone

70/377 (18.6)

21/160 (13.1)

58/343 (16.9)

15/130 (11.5)

51/340 (15.0)

17/180 (9.4)

 Highest daily dose, mga

100 (67–133)

71 (50–133)

75 (50–100)

50 (50–100)

63 (50–100)

50 (50–75)

 Duration, daysb

6 (4–9)

6 (4–8)

5 (3–9)

6 (3–9)

4 (2–7)

4 (3–8)

Antibiotic treatment

363/378 (96.0)

143/153 (93.5)

309/330 (93.6)

125/128 (97.7)

268/323 (83.0)

147/173 (85.0)

 Duration, days

7 (5–9)

7 (4–10)

7 (5–11)

7 (4–9)

7 (4–9)

6 (4–9)

Prone positioning

263/401 (65.6)

120/166 (72.3)

96/349 (27.5)

55/132 (41.7)

33/340 (9.7)

30/182 (16.5)

ECMO

39/402 (9.7)

22/165 (13.3)

38/349 (10.9)

22/131 (16.8)

2/341 (0.6)

3/182 (1.6)

  1. Vales are no./No. (%) or median (interquartile range)
  2. ECMO, Extracorporeal Membrane Oxygenation; ICU, Intensive Care Unit; MV, Mechanical Ventilation
  3. a11 missing values (SARS-CoV-2, n = 4; influenza, n = 4; controls, n = 3); b16missing values (SARS-CoV-2, n = 7; influenza, n = 3; controls, n = 6)