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Table 1 General characteristics of the study cohort at inclusion

From: Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial

Variable

Control group

Prone group

Count

39

36

Male

32 (82%)

23 (64%)

Age

65 [55–70]

66 [53–74]

BMI

29 [27–33]

28 [25–30]

Obesity (BMI ≥ 30 kg m−2)

12 (32%)

8 (23%)

Hypertension

21 (55%)

17 (47%)

Ischemic cardiac disease

5 (13%)

6 (17%)

Congestive heart failure

6 (15%)

2 (6%)

Lung disease

10 (26%)

4 (11%)

Asthma

5 (13%)

1 (3%)

COPD

4 (10%)

2 (6%)

Fibrosis

0 (0%)

1 (3%)

Sarcoidosis

1 (3%)

0 (0%)

Diabetes mellitus

11 (28%)

14 (39%)

Renal diseasea

2 (5%)

3 (8%)

Active cancer

1 (3%)

4 (11%)

Liver disease

1 (3%)

0 (0%)

Enrollment outside ICU

20 (51%)

19 (53%)

HFNO

29 (74%)

31 (86%)

Flow rate (HFNO)

50 [40–50]

50 [40–50]

PEEP (NIV)

8 [6–8]

7 [6–10]

FiO2

0.6 [0.55–0.70]

0.6 [0.55–0.70]

SpO2

94 [92–95]

93 [91–94]

PaO2

9.2 [8.2–10]

8.8 [7.7–9.7]

RR

26 [23–32]

24 [21–29]

PaO2/FiO2 ratio

15.4 [12.5–17.3]

15.4 [11.5–17.4]

SpO2/FiO2 ratio

157 [136–175]

151 [131–174]

SBP

130 [120–140]

130 [120–140]

DBP

70 [60–80]

69 [62–75]

  1. Categorical parameters are presented as n (%), continuous variables as median (interquartile range [IQR]); COPD, Chronic obstructive pulmonary disease; BMI, Body Mass Index; ICU, Intensive Care Unit; HFNO High-flow Nasal Oxygen; PEEP, Positive End Expiratory Pressure; NIV Noninvasive ventilation; RR, Respiratory Rate; SBP, Systolic Blood Pressure; DBP, Diastolic Blood Pressure
  2. aCreatinine clearance < 60 mL min−1