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Table 2 Cox proportional hazard regression model for overall survival of COVID-19 patients

From: The predicting roles of carcinoembryonic antigen and its underlying mechanism in the progression of coronavirus disease 2019

Variable

Overall survival (OS)

Hazard ratio (95% CI)

P

Categorical age

  

 < 40

1.00 (reference)

 

40–60

1.791 (0.212 to 15.119)

0.592

 > 60

2.118 (0.258 to 17.384)

0.485

Gender

  

Female

1.00 (reference)

 

Male

1.727 (1.154 to 2.585)

0.008*

Shortness of breath

  

No

1.00 (reference)

 

Yes

1.697 (1.054 to 2.731)

0.029*

Hypertension

  

No

1.00 (reference)

 

Yes

1.271 (0.853 to 1.893)

0.239

Cerebral infarction

  

No

1.00 (reference)

 

Yes

1.999 (0.921 to 4.342)

0.080

Imaging score

  

1.0–2.0

1.00 (reference)

 

3.0–4.0

0.638 (0.127 to 3.191)

0.584

5.0–6.0

0.472 (0.092 to 2.421)

0.368

7.0–8.0

0.603 (0.120 to 3.027)

0.539

Mode of ventilation

  

No oxygen

1.00 (reference)

 

OWNC

0.713 (0.058 to 8.810)

0.792

HFNC

8.181 (0.702 to 95.353)

0.093

NIV

18.714 (1.584 to 221.082)

0.020*

IV

21.148 (1.809 to 247.183)

0.015*

Categorical CEA

  

 > 7.3

1.00 (reference)

 

0–7.3

0.570 (0.354 to 0.917)

0.020*

Albumin (g/l)

  

 < 30

1.00 (reference)

 

30–35

0.894 (0.550 to 1.454)

0.653

35–40

0.594 (0.285 to 1.240)

0.164

 > 40

0.595 (0.072 to 4.937)

0.630

Neutrophils (× 109/l)

  

 < 1.8

1.00 (reference)

 

1.8–6.3

0.739 (0.162 to 3.370)

0.696

 > 6.3

0.630 (0.140 to 2.788)

0.538

Lymphocytes (× 109/l)

  

 < 1.1

1.00 (reference)

 

1.1–3.2

1.343 (0.773 to 2.332)

0.296

CRP (mg/l)

  

 > 160

1.00 (reference)

 

0–6

0.686 (0.056 to 8.457)

0.768

6–160

0.683 (0.452 to 1.023)

0.064

Hypokalemia

  

No

1.00 (reference)

 

Yes

1.068 (0.656 to 1.737)

0.792