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Table 1 Total vitamin C and DHA in plasma samples of critically ill patients receiving vitamin C therapy. Data from [32]

From: Measuring vitamin C in critically ill patients: clinical importance and practical difficulties—Is it time for a surrogate marker?

Bolus dosing regimen T = 1 T = 2
2 g (n = 5) 10 g (n = 5) 2 g (n = 5) 10 g (n = 5)
Total vitamin C, μmol/l 174 [163.8–254.8] 1101 [1067.5–1287.6] 136.1 [97.2–203.3] 733.1 [703.2–879.6]
DHA, μmol/l 12.7 [7.5–25.6] 100.3 [61.9–113.2] 8.7 [3.3–24.8] 63.6 [31.2–69.5]
DHA, % of Tot (95% CI) 7.7 (2.8–12.7) 7.7 (4.1–11.2) 8.8 (0.8–16.8) 6.8 (3.6–10.0)
Continuous dosing regimen T = 24 T = 48
2 g (n = 5) 10 g (n = 5) 2 g (n = 5) 10 g (n = 5)
Total vitamin C, μmol/l 101.4 [15.8–134.9] 428.3 [352.8–612] 108.2 [42.0–174.1] 453.5 [318.9–1230.8]
DHA, μmol/l 11.7 [1.5–18.3] 31.9 [15.2–48.7] 8.4 [4.2–18.9] 18.6 [9.1–50.3]
DHA, % of Tot (95% CI) 13.7 (5.3–22.0) 6.5 (3.1–9.9) 10.2 (2.5–17.9) 4.2 (0.1–8.3)
  1. Data are presented as median [IQR]