Table 1 Characteristics of individual patients at day of blood volume measurement
From: Blood volume and albumin transudation in critically ill COVID-19 patients
Parameter at time of measurement | Pat 1 #S | Pat 2 %#NS | Pat 3 NS | Pat 4 NS | Pat 5 #NS | Pat 6 S | Mean ± SD Median IQR |
|---|---|---|---|---|---|---|---|
ICU Admission | March 2020 | March 2020 | April 2020 | April 2020 | April 2020 | April 2020 | |
Day of ICU admission at measurement | 14 | 20 | 11 | 13 | 7 | 2 | |
Age|male/female | 70|M | 69|M | 49|M | 62|M | 66|F | 81|M | 66 ± 11 68 (59–73) |
Height (cm) | 1.75 | 1.73 | 1.65 | 1.73 | 1.58 | 1.52 | 166 ± 0.09 | 1.69 (1.57–1.74) |
Weight (kg) | 76.2 | 78.0 | 77.8 | 67.8 | 93.9 | 61.8 | 75.9 ± 10.9 | 77.0 (66.3–82.0) |
Ideal body weight (kg) | 70.0 | 69.0 | 61.0 | 69.0 | 51 | 50.0 | 61.7 ± 9.2 | 65.0 (50.8–69.3) |
Heart rate (b/min) | 95 | 104 | 97 | 69 | 112 | 72 | 92 ± 17 96 (71–106) |
Systolic arterial pressure (mmHg) | 137 | 72 | 97 | 94 | 146 | 96 | 107 ± 28 97 (89–138) |
Diastolic arterial pressure (mmHg) | 56 | 38 | 66 | 48 | 52 | 42 | 50 ± 10 50 (41–59) |
Mean arterial pressure (mm Hg) | 79 | 50 | 76 | 66 | 75 | 58 | 67 ± 11 71 (56–77) |
Lactate (mmol/L) | 1.5 | 1.6 | 1.3 | 2.5 | 1.8 | 1.4 | 1.7 ± 0.4 1.6 (1.4–2.0) |
C reactive protein at measurement (mg/L) | 3 | 239 | 409 | 282 | 263 | 50 | 208 ± 153 251 (38–313) |
Inspired oxygen fraction | 0.4 | 0.8 | 0.7 | 1 | 0.8 | 0.4 | 0.68 ± 0.24 0.75 (0.4–0.9) |
Pulse oximetry (%) | 97 | 95 | 96 | 95 | 91 | 96 | 95 ± 2 96 (94–97) |
Net fluid balance day before measurement (L) | − 0.9 | 1.2 | 1.3 | − 0.3 | − 0.9 | 3.0 | 0.6 ± 1.5 0.45 (− 0.9 to 1.7) |
Fluids IN day before measurement (L) | 3.6 | 2.1 | 2.6 | 1.7 | 3.1 | 3.2 | 2.7 ± 0.7 2.9 (2.0–3.3) |
Urine output day before measurement (L) | 4.5 | 0.7 | 0.8 | 2.7 | 1.8 | 0.7 | 1.9 ± 1.5 1.3 (0.7–3.2) |
Fluids in since admission (L) | 36.8 | 41 | 17.2 | 19.8 | 15.4 | 3.8 | 22.3 ± 14.0 18.5 (12.5–37.9) |
Net fluid balance since admission (L) | 8.2 | 10 | 5.9 | 3.0 | 0.3 | 4.0 | 5.2 ± 3.5 5.0 (2.3–8.7) |
Clinical assessment of volume status | Hyper | Hyper | Eu | Hyper | Hyper | Hypo | |
Total blood volume (mL) | 4200 | 4290 | 5360 | 3990 | 4870 | 4552 | 4544 ± 502 4421 (4223–4791) |
Red cell volume (mL) | 1215 | 935 | 1391 | 841 | 1220 | 1370 | 1162 ± 227 1218 (1005–1333) |
Plasma volume (mL) | 2985 | 3355 | 3969 | 3149 | 3650 | 3182 | 3382 ± 366 3269 (3157–3576) |
Total blood volume dev (%) | − 16.6 | − 17.3 | − 15.2 | − 18.9 | + 3.3 | + 17.2 | − 7.9 ± 14.8 − 15.9 (− 17.7 to 6.8) |
Red cell volume dev (%) | − 41% | − 56% | − 26% | − 58% | − 28% | − 13% | − 34 (− 56 to − 23) |
Plasma volume dev (%) | − 0% | 9% | 44% | 8% | 21% | 38% | 15% (6–39) |
Albumin transudation rate (%/min) | 0.58 | 0.82 | 0.43 | 0.49 | 0.24 | 0.12 | 0.45 ± 0.25 0.46 (0.21–0.64) |