Table 2 Clinical outcomes and electrolyte profiles dichotomized by time-period
Outcomes | Pre-intervention n = 1483 | Post-intervention n = 1380 |
|---|---|---|
Acute kidney injury (day 3) n = 1008 | ||
n (%) | 66 (13%) | 64 (12.5%) |
Unadjusted OR | Ref | 0.93 95% CI: 0.64–1.34 |
Adjusted OR | Ref | 0.96 95% CI: 0.65–1.42 |
Severe AKI (day 3) n = 1008 | ||
n (%) | 34 (6.9%) | 38 (7.4%) |
Unadjusted OR | Ref | 1.08 95% CI: 0.67–1.75 |
Adjusted OR | Ref | 1.17 95% CI: 0.71–1.93 |
Mortality | ||
n (%) | 39 (2.6%) | 40 (2.9%) |
Unadjusted OR | Ref | 1.11 95% CI: 0.71–1.73 |
Adjusted OR | Ref | 1.34 95% CI: 0.78–2.31 |
Need for renal replacement therapy | ||
n (%) | 15 (1.1%) | 24 (1.8%) |
Unadjusted OR | Ref | 1.65 95% CI: 0.86–3.16 |
Adjusted OR | Ref | 1.9 95% CI: 0.94–3.82 |
Hospital length of stay (days) | ||
Med (IQR) | 4.9 (2.9–9.7) | 5.5 (3–11.25) |
Unadjusted OR | Ref | 1.03 95% CI: 1.01–1.06 |
Adjusted OR | Ref | 1.00 95% CI: 0.98–1.02 |
Ventilator-free days | ||
Med (IQR) | 28 (26–28) | 28 (25–28) |
Unadjusted OR | Ref | 0.99 95% CI: 0.97–1.00 |
Adjusted OR | Ref | 1.00 95% CI: 0.98–1.01 |
> 10% Fluid overload on day 3 n = 1008 | ||
n (%) | 256 (22%) | 355 (30.1%) |
Unadjusted OR | Ref | 1.54 95% CI: 1.28–1.86 |
Adjusted OR | Ref | 1.56 95% CI: 1.28–1.90 |
Hyperchloremia | ||
n (%) | 119 (15.5%) | 81 (10.4%) |
Unadjusted RR | Ref | 0.66 95% CI: 0.51–0.87 |
Adjusted RR | Ref | 0.68 95% CI: 0.53–0.89 |
Hypochloremia | ||
n (%) | 73 (9.5%) | 112 (14.4%) |
Unadjusted RR | Ref | 1.51 95% CI: 1.14–1.99 |
Adjusted RR | Ref | 1.49 95% CI: 1.14–1.96 |
Hyperkalemia | ||
n (%) | 25 (3.2%) | 11 (1.4%) |
Unadjusted RR | Ref | 0.43 95% CI: 0.21–0.87 |
Adjusted RR | Ref | 0.42 95% CI: 0.21–0.85 |
Hypokalemia | ||
n (%) | 296 (38.2%) | 373 (47.2%) |
Unadjusted RR | Ref | 1.23 95% CI: 1.10–1.38 |
Adjusted RR | Ref | .23 95% CI: 1.10–1.37 |