| Control | EPA | HMB | HMB + EPA | P values |
---|---|---|---|---|---|
(n = 20) | (n = 17) | (n = 18) | (n = 18) | ||
Mean | Mean | Mean | Mean | ||
(95% CI) | (95% CI) | (95% CI) | (95% CI) | ||
Age (years) | 55.5 | 52.9 | 61.2 | 56.2 | 0.384 |
(47.7–63.1) | (46.0–59.7) | (54.0–68.4) | (49.7–62.7) | ||
Weight (kg) | 86.5 | 89.3 | 93.7 | 83.8 | 0.714 |
(76.0–96.9) | (75.8–102.8) | (81.3–106.0) | (67.6–99.9) | ||
SOFA | 7.0 | 7.7 | 6.7 | 8.1 | 0.619 |
(5.3–8.7) | (6.0–9.4) | (5.3–8.1) | (6.1–10.1) | ||
CCS | 4.0 | 3.0 | 3.6 | 2.9 | 0.483 |
(2.7–5.3) | (1.6–4.4) | (2.4–4.7) | (1.9–3.9) | ||
Prior MV duration (days) | 9.2 | 8.8 | 7.5 | 7.3 | 0.875 |
(4.7–13.6) | (5.1–12.4) | (4.0–11.0) | (3.1–11.5) | ||
Systolic BP (mm Hg) | 119 | 115 | 120 | 119 | 0.836 |
(111–127) | (106–124) | (112–129) | (110–128) | ||
Diastolic BP (mm Hg) | 68 | 61 | 63 | 68 | 0.344 |
(61–74) | (53–69) | (56–70) | (62–73) | ||
Heart rate (beats/min) | 87.3 | 90.9 | 82.4 | 93.6 | 0.264 |
(78.5–96.0) | (81.8–100.1) | (74.4–90.5) | (84.9–102.2) | ||
Temp (°F) | 99.1 | 99.2 | 99.2 | 98.4 | 0.134 |
(98.5–99.8) | (98.6–99.8) | (98.5–99.9) | (97.8–98.9) | ||
Respirations (breaths/min) | 22.3 | 23.1 | 20.0 | 21.5 | 0.289 |
(19.4–25.1) | (20.2–26.1) | (17.2–22.1) | (18.9–24.1) |  | |
FiO2 | 0.43 | 0.52 | 0.44 | 0.45 | 0.149 |
(0.39–0.48) | (0.44–0.58) | (0.38–0.49) | (0.41–0.49) | ||
PEEP (cm H2O) | 5.9 | 8.3 | 6.2 | 6.4 | 0.056 |
(5.1–6.7) | (6.2–10.4) | (4.9–7.5) | (5.1–7.8) | ||
Static compliancea | 26.0 | 23.0 | 23.2 | 24.0 | 0.673 |
(21.3–30.8) | (19.1–26.9) | (20.1–26.3) | (19.5–28.4) | ||
Airway resistanceb | 10.7 | 10.0 | 14.8 | 12.5 | 0.128 |
(8.7–12.7) | (6.9–13.1) | (10.1–19.5) | (9.9–15.2) | ||
Number of doses | 19.0 | 18.2 | 17.8 | 17.0 | 0.465 |
(18.1–19.9) | (15.7–20.7) | (15.9–19.7) | (14.8–19.2) | ||
Number of PT-OT sessions | 2.6 | 2.6 | 1.8 | 2.9 | 0.590 |
(1.3–3.9) | (1.5–3.7) | (0.8–2.8) | (1.4–4.3) | ||
Primary | Enteral | Enteral | Enteral | Enteral | Â |
Nutrition route | Tube feeding | Tube feeding | Tube feeding | Tube feeding | |
Degree of dependence | Independent 55% | Independent 59% | Independent 61% | Independent 67% | Â |
Assistance 45% | Assistance 41% | Assistance 39% | Assistance 33% | ||
Main diagnoses | Respiratory failure 35% | Respiratory failure 53% | Respiratory failure 56% | Respiratory failure 50% | Â |
Sepsis 45% | Sepsis 41% | Sepsis 44% | Sepsis 56% | ||
Pneumonia 60% | Pneumonia 53% | Pneumonia 33% | Pneumonia 39% |