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Table 1 Patient demographics

From: A randomized controlled trial to determine whether beta-hydroxy-beta-methylbutyrate and/or eicosapentaenoic acid improves diaphragm and quadriceps strength in critically Ill mechanically ventilated patients

 

Control

EPA

HMB

HMB + EPA

P values

(n = 20)

(n = 17)

(n = 18)

(n = 18)

Mean

Mean

Mean

Mean

(95% CI)

(95% CI)

(95% CI)

(95% CI)

Age (years)

55.5

52.9

61.2

56.2

0.384

(47.7–63.1)

(46.0–59.7)

(54.0–68.4)

(49.7–62.7)

Weight (kg)

86.5

89.3

93.7

83.8

0.714

(76.0–96.9)

(75.8–102.8)

(81.3–106.0)

(67.6–99.9)

SOFA

7.0

7.7

6.7

8.1

0.619

(5.3–8.7)

(6.0–9.4)

(5.3–8.1)

(6.1–10.1)

CCS

4.0

3.0

3.6

2.9

0.483

(2.7–5.3)

(1.6–4.4)

(2.4–4.7)

(1.9–3.9)

Prior MV duration (days)

9.2

8.8

7.5

7.3

0.875

(4.7–13.6)

(5.1–12.4)

(4.0–11.0)

(3.1–11.5)

Systolic BP (mm Hg)

119

115

120

119

0.836

(111–127)

(106–124)

(112–129)

(110–128)

Diastolic BP (mm Hg)

68

61

63

68

0.344

(61–74)

(53–69)

(56–70)

(62–73)

Heart rate (beats/min)

87.3

90.9

82.4

93.6

0.264

(78.5–96.0)

(81.8–100.1)

(74.4–90.5)

(84.9–102.2)

Temp (°F)

99.1

99.2

99.2

98.4

0.134

(98.5–99.8)

(98.6–99.8)

(98.5–99.9)

(97.8–98.9)

Respirations (breaths/min)

22.3

23.1

20.0

21.5

0.289

(19.4–25.1)

(20.2–26.1)

(17.2–22.1)

(18.9–24.1)

 

FiO2

0.43

0.52

0.44

0.45

0.149

(0.39–0.48)

(0.44–0.58)

(0.38–0.49)

(0.41–0.49)

PEEP (cm H2O)

5.9

8.3

6.2

6.4

0.056

(5.1–6.7)

(6.2–10.4)

(4.9–7.5)

(5.1–7.8)

Static compliancea

26.0

23.0

23.2

24.0

0.673

(21.3–30.8)

(19.1–26.9)

(20.1–26.3)

(19.5–28.4)

Airway resistanceb

10.7

10.0

14.8

12.5

0.128

(8.7–12.7)

(6.9–13.1)

(10.1–19.5)

(9.9–15.2)

Number of doses

19.0

18.2

17.8

17.0

0.465

(18.1–19.9)

(15.7–20.7)

(15.9–19.7)

(14.8–19.2)

Number of PT-OT sessions

2.6

2.6

1.8

2.9

0.590

(1.3–3.9)

(1.5–3.7)

(0.8–2.8)

(1.4–4.3)

Primary

Enteral

Enteral

Enteral

Enteral

 

Nutrition route

Tube feeding

Tube feeding

Tube feeding

Tube feeding

Degree of dependence

Independent 55%

Independent 59%

Independent 61%

Independent 67%

 

Assistance 45%

Assistance 41%

Assistance 39%

Assistance 33%

Main diagnoses

Respiratory failure 35%

Respiratory failure 53%

Respiratory failure 56%

Respiratory failure 50%

 

Sepsis 45%

Sepsis 41%

Sepsis 44%

Sepsis 56%

Pneumonia 60%

Pneumonia 53%

Pneumonia 33%

Pneumonia 39%

  1. Bold was used to highlight the groups, means and P values
  2. Italics represents the n = number of subjects per group and the 95% confidence interval
  3. CI = Confidence interval, SOFA = sequential organ failure score, CCS = Charlson comorbidity score, MV = mechanical ventilation, BP = blood pressure, mm Hg = millimeters of mercury, F = Fahrenheit, FiO2 = fraction of inspired oxygen, PEEP = positive end expiratory pressure, H2O = water, PT = physical therapy, OT = occupational therapy
  4. aRespiratory system static compliance (ml/cm H2O)
  5. bAirway resistance (cm H2O/liter/second)