Table 1 Patient and infection characteristics at the time of inclusion
N = 18 | |
|---|---|
Age | 69 (61–75) |
Male sex | 13 (72%) |
Smoking history | 10 (56%) |
Diabetes | 3 (17%) |
Hypertension | 11 (61%) |
Chronic pulmonary disease | 4 (22%) |
Immunosuppression | 3 (17%) |
Charlson index ≥ 2points | 6 (33%) |
Body mass index | |
< 25 | 3 (17%) |
25–30 | 8 (44%) |
30–35 | 1 (6%) |
35 + | 6 (33%) |
Infection characteristics | |
Symptom duration, days | 13 (10–14) |
Respiratory rate/minute | 24 (21–28) |
Heart rate/minute | 69.5 (64–87) |
MAP, mmHg | 90 (84–103) |
PaO2, KPa/mmHg | 8.1 (7.0–8.8) / 61 (53–66) |
Estimated P/F ratio, KPa/mmHg | 9.8 (8.4–10.5) / 74 (63–79) |
c-Reactive protein, mg/L | 74 (41–111) |
Neutrofile/lymphocyte ratio | 12 (7–21) |
Procalcitonin, μg/L | 0.2 (0.1–0.3) |
Ferritin, μg/L | 1085 (752–1683) |
d-Dimer, mg/L | 1.9 (0.8–3.6) |
Troponin, ng/L | 12 (9–21) |
Pro-BNP, ng/L | 466 (235–1197) |
Creatinine, µmol/L | 65 (59–73) |
Treatment | |
Betametasone | 18 (100%) |
LMWH | 18 (100%) |
Remdesivir | 1 (6%) |
Antibiotics | 6 (33%) |
HFNC flow, L/min | 40 (40–40) |
FiO2, % | 82.5% (80–100) |
Position (side/back/prone) | 9/4/5 |
HFNC/NIV ceiling of care | 4 (22%) |