Acute cor pulmonale in Covid-19 related acute respiratory distress syndrome

Table 2 Univariate and multivariable analysis for acute cor pulmonale in patients with Cocid-19 related acute respiratory distress syndrome

	N patients with data	Univariate analysis	Multivariable analysis
Patient characteristics*
Body mass index (kg/m²)	113	1.07 [0.996–1.14], p = 0.06	NR
Medical history*
Diabetes	117	0.34 [0.15–0.78], p = 0.01	NR
Chronic kidney disease	117	0.16 [0.03–0.71], p = 0.02	NS
Respiratory parameters*
Respiratory system compliance (mL/cmH₂O)	102	1.02 [0.99 -1.05], p = 0.27	NS
CT-scan
Pulmonary embolism	81	8.5 [1.63–44.33], p = 0.01	7.30 [1.32–40.29], p = 0.02

Data presented as OR [95% CI]; OR—Odds Ratio, 95% CI—95% Confidence Interval, NS—not significant in the final model, NR—not retained in the final model; The multivariable model showed a good calibration as assessed by the Hosmer and Lemeshow goodness of fit test [X²(8 df) = 7.8, p = 0.45] and a fair discrimination as assessed by the receiver operating characteristics curve [area under the curve (AUC) 0.779; 95% CI 0.673–0.885; p < 0.0001]

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