Table 2 Estimated odds ratios (ORs) and confidence intervals of important variables in a multivariate logistic model predicting the onset of hypoglycemia (blood glucose ≤ 70 mg/dL) within 6 h

BMI [0–18.5] kg/m²

1.6

(1.43–1.79)

1.61

(1.28–2.03)

1.58

(1.35–1.86)

BMI [18.5–25] kg/m²

1

(–)

1

(–)

1

(–)

BMI [25–30] kg/m²

0.72

(0.67–0.77)

0.74

(0.65–0.85)

0.68

(0.62–0.74)

BMI [30–35] kg/m²

0.65

(0.6–0.71)

0.63

(0.52–0.76)

0.59

(0.53–0.66)

BMI [35–40] kg/m²

0.61

(0.54–0.69)

0.46

(0.32–0.65)

0.58

(0.5–0.66)

BMI > 40 kg/m²

0.53

(0.46–0.61)

0.83

(0.48–1.41)

0.44

(0.38–0.51)

Blood glucose [70–108] mg/dL

1

(–)

1

(–)

1

(–)

Blood glucose [108–144] mg/dL

0.3

(0.28–0.32)

0.26

(0.22–0.29)

0.34

(0.31–0.37)

Blood glucose [144–180] mg/dL

0.26

(0.24–0.28)

0.18

(0.15–0.21)

0.34

(0.3–0.38)

Blood glucose > 180 mg/dL

0.29

(0.26–0.32)

0.18

(0.15–0.22)

0.35

(0.31–0.39)

Insulin = 0 u/h

1

(–)

1

(–)

1

(–)

Insulin [0–2.5] u/h

2.18

(2.01–2.35)

3.02

(2.58–3.52)

1.32

(1.17–1.49)

Insulin [2.5–5] u/h

5.07

(4.69–5.48)

6.97

(5.87–8.28)

3.47

(3.12–3.87)

Insulin > 5 u/h

6.41

(5.87–7)

8.76

(7.11–10.79)

4.17

(3.73–4.66)

Blood lactate [0–2] mmol/L

1

(–)

1

(–)

1

(–)

Blood lactate [2–5] mmol/L

1.6

(1.48–1.73)

1.45

(1.25–1.7)

1.8

(1.62–2)

Blood lactate > 5 mmol/L

3.24

(2.86–3.68)

3.79

(3.03–4.74)

3.63

(3.03–4.35)

MAP ≥ 60 mmHg, no vasopressor therapy

1

(–)

1

(–)

1

(–)

MAP < 60 mmHg or vasopressor therapy

1.48

(1.39–1.57)

1.41

(1.24–1.6)

1.56

(1.43–1.69)

Parenteral nutrition

0.66

(0.58–0.76)

0.68

(0.52–0.89)

0.75

(0.61–0.92)

Enteral nutrition

0.83

(0.78–0.89)

0.62

(0.55–0.71)

1.11

(1.02–1.21)

Corticosteroids

0.85

(0.77–0.94)

0.81

(0.67–0.98)

0.95

(0.84–1.08)

Dextrose 10% 0 mL/h

1

(–)

1

(–)

1

(–)

Dextrose 10% < 25 mL/h

1.06

(0.74–1.52)

0.8

(0.37–1.72)

1.03

(0.69–1.56)

Dextrose 10% > 25 mL/h

2.04

(1.75–2.37)

2

(1.57–2.55)

1.92

(1.51–2.44)

Diabetes

–

–

2.21

(2.04–2.4)

SOFA*

1.07

(1.06–1.08)

1.04

(1.01–1.06)

1.07

(1.06–1.09)

AUMC

1

(–)

1

(–)

–

HiRID

0.43

(0.39–0.48)

0.66

(0.58–0.74)

–

MIMIC–III

0.92

(0.86–0.99)

–

1

(–)

eICU

1.51

(1.38–1.65)

–

2.19

(2–2.4)