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Table 2 Respiratory mechanics and arterial blood gas

From: Response to PEEP in COVID-19 ARDS patients with and without extracorporeal membrane oxygenation. A multicenter case–control computed tomography study

Variables

Whole dataset (n = 99)

Moderate ARDS without ECMO (n = 16)

Severe ARDS without ECMO (n = 59)

Severe ARDS on ECMO (n = 24)

PEEP—cmH2O

10 [5–14]

9 [5–10]

10 [5–10]

15 [13–15] a,b

VT—mL.kg−1 PBW

5.9 [3.9–6.0]

6.0 [5.9–6.0]

6.0 [5.9–6.0]

1.0 [1.0–1.0] a,b

RR—min−1

22 [16–28]

23 [20–28]

25 [22–29]

5 [5–10] a,b

PEEPtot,rs—cmH2O

10 [7–15]

9 [6–10]

10 [6–11]

15 [14–15] a,b

Pplat,rs—cmH2O

20 [17–22]

18 [17–24]

20 [16–23]

20 [19–21]

Ppeak—cmH2O

29 [25–35]

30 [28–34]

32 [27–37]

22 [21–24] a,b

ΔPrs—cmH2O

9 [7–12]

10 [9–13]

10 [9–12]

5 [3–8] a,b

Ers—cmH2O. L−1

33 [25–44]

29 [22–37]

28 [23–35]

70 [53–95] a,b

pH

7.38 [7.32–7.44]

7.37 [7.33–7.42]

7.37 [7.31–7.41]

7.46 [7.39–7.47] a,b

PaO2—Torr

72 [65–80]

78 [67–89]

74 [66–80]

69 [62–74] a

FiO2 or FmO2 – %

90 [60–100]

50 [44–53]

90 [65–100] a

100 [80–100] a

PaCO2—Torr

49 [41–54]

42 [37–51]

50 [43–58]

49 [41–51]

Bicarbonates—mmol.L−1

28 [24–32]

26 [22–28]

27 [24–31]

32 [29–34] a,b

Lactate—mmol.L−1

1.7 [1.3–2.2]

1.5 [1.3–1.9]

1.6 [1.3–2.2]

1.9 [1.6–2.4]

  1. Values are median [1st quartile–3rd quartile], a p < 0.05 vs. moderate ARDS without ECMO. b p < 0.05 vs. severe ARDS without ECMO
  2. ARDS acute respiratory distress syndrome, ΔPrs, driving pressure of the respiratory system, ECMO extracorporeal membrane oxygenation, Ers elastance of the respiratory system, FiO2 inspired fraction of oxygen, FmO2, ECMO membrane oxygen fraction, PaCO2 carbon dioxide partial pressure in arterial blood, PaO2 oxygen partial pressure in arterial blood, PBW predicted body weight, PEEP positive end-expiratory pressure, PEEPtot,rs total PEEP of the respiratory system, Ppeak peak airway pressure, Pplat,rs plateau pressure of the respiratory system, RR respiratory rate, VT tidal volume