Table 1 Characteristics for patients with PaO2/FiO2 ≤ 20 kPa on invasive mechanical ventilation within 24 h from ICU admission
All | Early prone = NO | Early prone = YES | |
|---|---|---|---|
Patient demographics, characteristics and comorbidities at ICU admission | |||
No. (%) | 1714 | 1144 (66.7) | 570 (33.3) |
Women | 512 (29.9) | 346 (30.2) | 166 (29.2) |
Age, median (IQR), y | 64 (55–71) | 64 (55–71) | 64 (54–71) |
Age, Interval, y | |||
< 40 | 85 (5) | 61 (5.3) | 24 (4.2) |
40–49 | 175 (10.2) | 117 (10.2) | 58 (10.2) |
50–59 | 387 (22.6) | 254 (22.2) | 133 (23.3) |
60–69 | 549 (32) | 362 (31.6) | 187 (32.8) |
70–79 | 459 (26.8) | 309 (27) | 150 (26.3) |
≥ 80 | 59 (3.4) | 41 (3.6) | 18 (3.2) |
Admission month | |||
March – April 2020 | 514 (30) | 426 (37.2) | 88 (15.4) |
May – August 2020 | 228 (13.3) | 162 (14.2) | 66 (11.6) |
September – December 2020 | 326 (19) | 203 (17.7) | 123 (21.6) |
January – April 2021 | 646 (37.7) | 353 (30.9) | 293 (51.4) |
Location before ICU admission | |||
Emergency department | 398 (23.2) | 242 (21.2) | 156 (27.4) |
Hospital floor | 1316 (76.8) | 902 (78.8) | 414 (72.6) |
Time from symptom to ICU admission, median (IQR), d | |||
No. with data | 1688 | 1124 | 564 |
Median (IQR), d | 10 (7–13) | 10 (7–13) | 10 (8–14) |
Hospital level | |||
Tertiary | 576 (33.6) | 376 (32.9) | 200 (35.1) |
County | 964 (56.2) | 636 (55.5) | 328 (57.5) |
Local | 174 (10.2) | 132 (11.5) | 42 (7.4) |
Days at hospital before ICU admission | |||
Median (IQR), d | 2 (0–4) | 2 (0–4) | 2 (0–5) |
Pregnant, No | 16 | 14 | 2 |
Comorbidities | |||
None | 493 (28.8) | 356 (31.1) | 137 (24.0) |
One or more | 1221 (71.2) | 788 (68.9) | 433 (76.0) |
Chronic hypertension | 825 (48.1) | 521 (45.5) | 304 (53.3) |
Chronic cardiac disease | 239(13.9) | 162(14.2) | 77 (13.5) |
COPD/Asthma | 275 (16.0) | 178(15.6) | 97(17) |
Immune deficiency | 130 (7.6) | 77 (6.7) | 53 (9.3) |
Chronic liver disease | 12 (0.7) | 7 (0.6) | 5 (0.9) |
Chronic kidney disease | 97 (5.7) | 69 (6.0) | 28 (4.9) |
Diabetes | 484 (28.2) | 321 (28.1) | 163 (28.6) |
Neuromuscular disease | 18 (1.1) | 10 (0.9) | 8 (1.4) |
Obesitya | 188 (11.0) | 111 (9.7) | 77 (13.5) |
Malignancyb | 31 (1.8) | 21 (1.8) | 10 (1.8) |