Table 2 Multivariable logistic regression model of factors associated with the development of acute kidney injury (AKI) (n = 1699 patients)
Variable | Odds ratio | 95% confidence interval | p value |
|---|---|---|---|
Corticosteroid therapy | 0.74 | 0.63, 0.88 | < 0.001 |
Age (years) | 1.01 | 1.01, 1.02 | < 0.001 |
Sex (male) | 0.98 | 0.82, 1.16 | 0.78 |
Body mass index (kg/m2) | 1.01 | 0.99,1.02 | 0.19 |
Region (world high income vs Europe) | 1.40 | 1.14, 1.73 | 0.002 |
Region (world middle income vs Europe) | 1.57 | 1.16, 2.12 | 0.003 |
Comorbidity diabetes | 1.09 | 0.92,1.28 | 0.33 |
Hypertension | 1.26 | 1.07, 1.48 | 0.01 |
Malignant neoplasm | 1.05 | 0.73, 1.49 | 0.81 |
Cardiac disease | 1.22 | 0.99, 1.50 | 0.06 |
Respiratory failure (moderate vs mild) | 1.34 | 0.86, 2.10 | 0.20 |
Respiratory failure (severe vs mild) | 1.33 | 0.87, 2.03 | 0.19 |
Positive end-expiratory pressure (PEEP, cm H2O) | 1.00 | 0.98, 1.03 | 0.76 |
Extracorporeal membrane oxygenation (ECMO) support | 1.75 | 1.37, 2.24 | < 0.001 |
Tidal volume (mL) | 1.00 | 0.99, 1.01 | 0.58 |
Respiratory rate (breaths per minute) | 1.01 | 1.00. 1.03 | 0.01 |
Sequential organ failure assessment (platelets) | 0.96 | 0.85,1.07 | 0.46 |
Sequential organ failure assessment (cardiovascular) | 1.28 | 1.10,1.49 | < 0.001 |