Patients’ characteristics | All COVID-19 | J-shaped n = 126 | U-shaped n = 40 | Inverted J-shaped n = 18 | p value |
---|---|---|---|---|---|
Age, years, n = 184 | 60.04 ± 15.89 | 60.37 ± 15.94 | 59.20 ± 17.30 | 59.67 ± 12.68 | 0.915 |
Male, n (%), n = 184 | 127 (69.02%) | 92 (72.44%) | 25 (62.50%) | 10 (55.55%) | 0.160 |
Body mass index, kg/m2, n = 183 | 29.02 ± 6.43 | 27.48 ± 6.65a | 30.16 ± 6.95a,b | 35.89 ± 8.67b | < 0.001 |
Comorbidities, n (%), n = 69 | 44 (63.8%) | 30 (65.2%) | 11 (68.8%) | 3 (42.9%) | 0.500 |
Hypertension, n (%) | 38 (55.1%) | 24 (52.2%) | 11 (68.8%) | 3 (42.9%) | 0.422 |
Diabetes mellitus, n (%) | 29 (42%) | 18 (39.1%) | 8 (50%) | 3 (42.9%) | 0.807 |
SOFA, n = 143 | 5.43 ± 4.03 | 5.17 ± 3.04 | 5.69 ± 3.39 | 6.53 ± 3.06 | 0.262 |
PEEP at baseline n = 114 | 10 (10–14) | 10 (10–14)a,c | 12 (10–15.5)a | 15 (10.5–19.5)c | < 0.05 |
FiO2 at baseline, n (%), n = 184 | 80 (60–100) | 70 (60–100)a | 100 (70–100)a | 95 (60–100) | < 0.05 |
PaCO2 at baseline, mmhg, n = 75 | 51.6 ± 11.9 | 51.4 ± 11.1 | 54.2 ± 13.2 | 47.1 ± 14.4 | 0.410 |
Respiratory rate at baseline, breaths/min, n = 75 | 20 (20–25) | 20 (20–25) | 24 (20–24.5) | 20 (20–20) | 0.170 |
Minute ventilation at baseline, L/min, n = 75 | 8.1 ± 2.0 | 8.3 ± 2.0 | 8.1 ± 1.7 | 6.8 ± 1.7 | 0.180 |