From: The spectrum of sepsis-associated encephalopathy: a clinical perspective
 | Medical history | On ICU admission | During ICU stay |
---|---|---|---|
Non-modifiable factors | Older age Chronic kidney disease Chronic alcohol abuse History of neurologic disease History of cognitive impairment Long-term use of psychoactive drugs | Medical admission Mechanical ventilation Acute renal failure Bacteremia Staphylococcus aureus infection | Bacteremia |
Modifiable factors | – | Hypoglycemia < 3 mmol/l Hyperglycemia > 10 mmol/l Hypercapnia > 45 mmHg Hypernatremia > 145 mmol/l | Midazolam Cefepime |