Table 2 PbtO2-insult definitions in relation to favourable outcome and mortality
All | Favourable | Unfavourable | p | Survivor | Deceased | p | |
|---|---|---|---|---|---|---|---|
Median pbtO2 | 27 (21–33) | 28 (21–30) | 25 (20–31) | 0.06 | 27 (22–33) | 25 (19–31) | 0.09 |
Mean pbtO2 | 27 (22–33) | 28 (23–34) | 25 (21–32) | 0.045 | 28 (22–34) | 25 (19–31) | 0.07 |
%GMT below threshold | |||||||
pbtO2 < 10 mmHg (%) | 0 (0–2) | 0 (0–1) | 0 (0–4) | 0.008 | 0 (0–1) | 0 (0–4) | 0.17 |
pbtO2 < 15 mmHg (%) | 3 (0–15) | 2 (0–9) | 6 (0–19) | 0.008 | 3 (0–13) | 5 (0–22) | 0.11 |
pbtO2 < 20 mmHg (%) | 17 (4–43) | 12 (2–40) | 22 (4–53) | 0.02 | 15 (3–41) | 21 (4–56) | 0.13 |
pbtO2 < 25 mmHg (%) | 43 (14–74) | 35 (10–66) | 51 (19–76) | 0.046 | 40 (14–69) | 52 (14–85) | 0.12 |
pbtO2 < 30 mmHg (%) | 69 (39–93) | 64 (31–89) | 79 (46–96) | 0.051 | 67 (35–91) | 80 (45–97) | 0.08 |
pbtO2 < 35 mmHg (%) | 89 (63–99) | 84 (58–98) | 92 (65–99) | 0.06 | 86 (62–98) | 92 (71–100) | 0.09 |
pbtO2 < 40 mmHg (%) | 97 (79–100) | 96 (79–100) | 98 (81–100) | 0.12 | 97 (79–100) | 98 (87–100) | 0.14 |
Dose below threshold per hour | |||||||
pbtO2 < 10 mmHg (%) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.1) | 0.01 | 0.0 (0.0–0.0) | 0.0 (0.0–0.1) | 0.15 |
pbtO2 < 15 mmHg (%) | 0.1 (0.0–0.4) | 0.0 (0.0–0.2) | 0.1 (0.0–0.5) | 0.006 | 0.0 (0.0–0.3) | 0.1 (0.0–0.5) | 0.13 |
pbtO2 < 20 mmHg (%) | 0.5 (0.1–1.8) | 0.4 (0.1–1.4) | 0.9 (0.1–2.4) | 0.008 | 0.5 (0.1–1.5) | 0.6 (0.1–2.6) | 0.11 |
pbtO2 < 25 mmHg (%) | 2.0 (0.6–4.9) | 1.6 (0.4–4.1) | 2.4 (0.8–5.6) | 0.01 | 1.8 (0.6–4.3) | 2.4 (0.6–6.4) | 0.13 |
pbtO2 < 30 mmHg (%) | 4.8 (2.0–8.8) | 3.9 (1.4–7.9) | 5.7 (2.5–10.0) | 0.01 | 4.5 (2.0–8.4) | 5.9 (2.0–11.1) | 0.11 |
pbtO2 < 35 mmHg (%) | 8.6 (4.4–13.5) | 7.6 (3.7–12.7) | 10.2 (5.3–14.8) | 0.02 | 10.1 (5.3–14.8) | 10.0 (4.9–15.9) | 0.10 |
pbtO2 < 40 mmHg (%) | 13.1 (8.5–18.5) | 12.2 (7.5–17.6) | 14.8 (9.4–19.6) | 0.03 | 14.8 (9.5–19.6) | 14.6 (9.2–20.9) | 0.09 |