Table 3 Insult-combinations of pbtO₂ and ICP, PRx, CPP, and ∆CPPopt in relation to favourable outcome and mortality

ICP and pbtO₂, %GMT above/below threshold

ICP > 20 mmHg (%)

9 (2–32)

7 (2–28)

14 (2–36)

7 (2–28)

28 (5–58)

ICP > 20 mmHg and pbtO₂ < 15 mmHg (%)

0.2 (0.0–1.4)

0.2 (0.0–0.7)

0.2 (0.0–2.1)

0.1 (0.0–0.8)

0.8 (0.0–5.4)

ICP > 20 mmHg and pbtO₂ > 15 mmHg (%)

7 (2–22)

7 (2–20)

9 (1–23)

6 (2–18)

14 (3–34)

ICP < 20 mmHg and pbtO₂ < 15 mmHg (%)

1 (0–8)

1 (0–7)

2 (0–10)

1 (0–10)

1 (0–8)

PRx and pbtO₂, %GMT above/below threshold

PRx > 0.30 (%)

25 (17–36)

22 (16–32)

29 (20–48)

22 (16–32)

39 (26–64)

PRx > 0.30 and pbtO₂ < 15 mmHg (%)

0.5 (0.0–2.5)

0.4 (0.0–1.6)

0.9 (0.1–4.1)

0.4 (0.0–1.9)

1.6 (0.1–6.1)

PRx > 0.30 and pbtO₂ > 15 mmHg (%)

18 (11–27)

18 (12–23)

19 (11–30)

17 (11–23)

24 (15–44)

PRx < 0.30 and pbtO₂ < 15 mmHg (%)

0.9 (0.0–5.7)

1.0 (0.0–5.2)

0.8 (0.0–6.3)

1.0 (0.0–6.2)

0.8 (0.1–5.5)

CPP and pbtO₂, %GMT above/below threshold

CPP < 60 mmHg (%)

4 (2–8)

4 (2–7)

5 (2–10)

4 (2–7)

6 (3–15)

CPP < 60 mmHg and pbtO₂ < 15 mmHg (%)

0.1 (0.0–0.9)

0.1 (0.0–0.5)

0.2 (0.0–1.3)

0.1 (0.0–0.6)

0.3 (0.0–2.6)

CPP < 60 mmHg and pbtO₂ > 15 mmHg (%)

2 (1–5)

2 (1–4)

2 (1–5)

2 (1–4)

3 (1–9)

CPP > 60 mmHg and pbtO₂ < 15 mmHg (%)

1 (0–9)

1 (0–8)

2 (0–9)

1 (0–9)

2 (0–9)

∆CPPopt and pbtO₂, %GMT above/below threshold

∆CPPopt < −5 mmHg (%)

28 (22–37)

27 (20–32)

31 (24–42)

27 (20–32)

39 (26–52)

∆CPPopt < −5 mmHg and pbtO₂ < 15 mmHg (%)

0.3 (0.0–3.3)

0.2 (0.0–1.9)

0.5 (0.0–4.6)

0.2 (0.0–2.4)

0.6 (0.0–5.5)

∆CPPopt < −5 mmHg and pbtO₂ > 15 mmHg (%)

19 (11–24)

19 (11–24)

18 (9–24)

18 (11–24)

21 (12–27)

∆CPPopt > −5 mmHg and pbtO₂ < 15 mmHg (%)

1 (0–5)

1 (0–4)

0 (0–6)

1 (0–6)

1 (0–4)